Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 21405-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21405-1-AP, RRID:AB_10888630
- Product name
- APRT antibody
- Antibody type
- Polyclonal
- Description
- APRT antibody (Cat. #21405-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references 2,8-Dihydroxyadenine disrupts epithelial integrity and alters kidney cell phenotype in vitro.
Mechanistic insights into metformin's anti-hyperuricemic effect: Targeting PPP/DNPB/XOD-mediated purine pathway, purinosome assembly, and gut microbiota homostasis in rats.
Nuclear adenine activates hnRNPA2B1 to enhance antibacterial innate immunity.
Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas.
Thyroid Hormone-Regulated Expression of Period2 Promotes Liver Urate Production.
Helgudottir HR, Palsson R, Edvardsson VO, Gudjonsson T
Journal of molecular medicine (Berlin, Germany) 2026 Jan 6;104(1):23
Journal of molecular medicine (Berlin, Germany) 2026 Jan 6;104(1):23
Mechanistic insights into metformin's anti-hyperuricemic effect: Targeting PPP/DNPB/XOD-mediated purine pathway, purinosome assembly, and gut microbiota homostasis in rats.
Yu Q, Liao H, Tan W, Xu L, Lin G, Ai Z, Xie Q, Liu Y, Li Y, Yang X, Su Z, Ma G, Xie J, Lai Z
Chemico-biological interactions 2025 Nov 1;421:111783
Chemico-biological interactions 2025 Nov 1;421:111783
Nuclear adenine activates hnRNPA2B1 to enhance antibacterial innate immunity.
Zhang S, Cui Z, Zhang D, Zhang D, Jin K, Li Z, Li B, Cong B, Liu J, Wang L, Wen M, Cao X
Cell metabolism 2025 Feb 4;37(2):413-428.e7
Cell metabolism 2025 Feb 4;37(2):413-428.e7
Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas.
Yin J, Wang X, Ge X, Ding F, Shi Z, Ge Z, Huang G, Zhao N, Chen D, Zhang J, Agnihotri S, Cao Y, Ji J, Lin F, Wang Q, Zhou Q, Wang X, You Y, Lu Z, Qian X
Nature communications 2023 Sep 22;14(1):5913
Nature communications 2023 Sep 22;14(1):5913
Thyroid Hormone-Regulated Expression of Period2 Promotes Liver Urate Production.
Chen X, Wu M, Liang N, Lu J, Qu S, Chen H
Frontiers in cell and developmental biology 2021;9:636802
Frontiers in cell and developmental biology 2021;9:636802
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The APRT antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human APRT. This antibody recognizes human, mouse, rat antigen. The APRT antibody has been validated for the following applications: ELISA, WB analysis.