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- References [14]
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- Product number
- 12680-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12680-1-AP, RRID:AB_10640298
- Product name
- Protrudin antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Protrudin antibody (Cat. #12680-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Glucocorticoid enhances presenilin1-dependent Aβ production at ER's mitochondrial-associated membrane by downregulating Rer1 in neuronal cells.
Protrudin-mediated ER-endosome contact sites promote phagocytosis.
Transcription factor EB regulates phosphatidylinositol-3-phosphate levels that control lysosome positioning in the bladder cancer model.
ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology.
Protrudin regulates FAK activation, endothelial cell migration and angiogenesis.
A kinesin 1-protrudin complex mediates AMPA receptor synaptic removal during long-term depression.
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS.
ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic.
PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria.
Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry.
Protrudin modulates seizure activity through GABA(A) receptor regulation.
Fatty acid synthase cooperates with protrudin to facilitate membrane outgrowth of cellular protrusions.
Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia.
Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.
Choi GE, Park JY, Park MR, Yoon JH, Han HJ
Redox biology 2023 Sep;65:102821
Redox biology 2023 Sep;65:102821
Protrudin-mediated ER-endosome contact sites promote phagocytosis.
Elfmark LA, Wenzel EM, Wang L, Pedersen NM, Stenmark H, Raiborg C
Cellular and molecular life sciences : CMLS 2023 Jul 19;80(8):216
Cellular and molecular life sciences : CMLS 2023 Jul 19;80(8):216
Transcription factor EB regulates phosphatidylinositol-3-phosphate levels that control lysosome positioning in the bladder cancer model.
Mathur P, De Barros Santos C, Lachuer H, Patat J, Latgé B, Radvanyi F, Goud B, Schauer K
Communications biology 2023 Jan 28;6(1):114
Communications biology 2023 Jan 28;6(1):114
ERnet: a tool for the semantic segmentation and quantitative analysis of endoplasmic reticulum topology.
Lu M, Christensen CN, Weber JM, Konno T, Läubli NF, Scherer KM, Avezov E, Lio P, Lapkin AA, Kaminski Schierle GS, Kaminski CF
Nature methods 2023 Apr;20(4):569-579
Nature methods 2023 Apr;20(4):569-579
Protrudin regulates FAK activation, endothelial cell migration and angiogenesis.
Arora A, Kivelä AM, Wang L, Minkeviciene R, Taskinen JH, Zhang B, Koponen A, Sun J, Shirane M, Zhou Y, Hotulainen P, Raiborg C, Olkkonen VM
Cellular and molecular life sciences : CMLS 2022 Apr 4;79(4):220
Cellular and molecular life sciences : CMLS 2022 Apr 4;79(4):220
A kinesin 1-protrudin complex mediates AMPA receptor synaptic removal during long-term depression.
Brachet A, Lario A, Fernández-Rodrigo A, Heisler FF, Gutiérrez Y, Lobo C, Kneussel M, Esteban JA
Cell reports 2021 Aug 3;36(5):109499
Cell reports 2021 Aug 3;36(5):109499
Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS.
Petrova V, Pearson CS, Ching J, Tribble JR, Solano AG, Yang Y, Love FM, Watt RJ, Osborne A, Reid E, Williams PA, Martin KR, Geller HM, Eva R, Fawcett JW
Nature communications 2020 Nov 5;11(1):5614
Nature communications 2020 Nov 5;11(1):5614
ESCRT-III-associated proteins and spastin inhibit protrudin-dependent polarised membrane traffic.
Connell JW, Allison RJ, Rodger CE, Pearson G, Zlamalova E, Reid E
Cellular and molecular life sciences : CMLS 2020 Jul;77(13):2641-2658
Cellular and molecular life sciences : CMLS 2020 Jul;77(13):2641-2658
PDZD8 interacts with Protrudin and Rab7 at ER-late endosome membrane contact sites associated with mitochondria.
Elbaz-Alon Y, Guo Y, Segev N, Harel M, Quinnell DE, Geiger T, Avinoam O, Li D, Nunnari J
Nature communications 2020 Jul 20;11(1):3645
Nature communications 2020 Jul 20;11(1):3645
Selective EMC subunits act as molecular tethers of intracellular organelles exploited during viral entry.
Bagchi P, Torres M, Qi L, Tsai B
Nature communications 2020 Feb 28;11(1):1127
Nature communications 2020 Feb 28;11(1):1127
Protrudin modulates seizure activity through GABA(A) receptor regulation.
Lu X, Yang Y, Zhou R, Li Y, Yang Y, Wang X
Cell death & disease 2019 Nov 27;10(12):897
Cell death & disease 2019 Nov 27;10(12):897
Fatty acid synthase cooperates with protrudin to facilitate membrane outgrowth of cellular protrusions.
Zhang C, Lu J, Su H, Yang J, Zhou D
Scientific reports 2017 Apr 21;7:46569
Scientific reports 2017 Apr 21;7:46569
Protrudin regulates endoplasmic reticulum morphology and function associated with the pathogenesis of hereditary spastic paraplegia.
Hashimoto Y, Shirane M, Matsuzaki F, Saita S, Ohnishi T, Nakayama KI
The Journal of biological chemistry 2014 May 9;289(19):12946-61
The Journal of biological chemistry 2014 May 9;289(19):12946-61
Protrudin binds atlastins and endoplasmic reticulum-shaping proteins and regulates network formation.
Chang J, Lee S, Blackstone C
Proceedings of the National Academy of Sciences of the United States of America 2013 Sep 10;110(37):14954-9
Proceedings of the National Academy of Sciences of the United States of America 2013 Sep 10;110(37):14954-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ZFYVE27 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ZFYVE27. This antibody recognizes human,mouse,rat antigen. The ZFYVE27 antibody has been validated for the following applications: ELISA, WB analysis.
