Tissue expression
Cell line expression
Protein structure
MXD3
MAX dimerization protein 3bHLHc13, MAD3
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described. [provided by RefSeq, Dec 2008]
Top validated antibodies |
|||||
| Novus Biologicals | 1 references | Polyclonal |
|
||
| antibodies-online | 4 references | Polyclonal |
|
||
| St John's Laboratory | Polyclonal |
|
|||
| Antibodies.com | Polyclonal |
|
|||
| OriGene | Polyclonal |
|
|||