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- References [11]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 12525-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12525-1-AP, RRID:AB_2296127
- Product name
- IRF2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IRF2 antibody (Cat. #12525-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Dengue haemorrhagic fever: an evaluation of host innates immune factors in hepatic lesions and their correlation with immunopathogenesis.
Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue.
IRF2 Affects LPS- and IFN-γ-Induced Pro-Inflammatory Responses, Cell Viability, Migration and Apoptosis of Macrophages by Regulating IRG1.
Novel hypermorphic variants in IRF2BP2 identified in patients with common variable immunodeficiency and autoimmunity.
Lnc-PLCB1 is stabilized by METTL14 induced m6A modification and inhibits Helicobacter pylori mediated gastric cancer by destabilizing DDX21.
Long noncoding RNA SENCR facilitates the progression of acute myeloid leukemia through the miR-4731-5p/IRF2 pathway.
Analysis of miRNA Expression Profiling of RIP2 Knockdown in Chicken HD11 Cells When Infected with Avian Pathogenic E. coli (APEC).
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis.
IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3.
MicroRNA-664 functions as an oncogene in cutaneous squamous cell carcinomas (cSCC) via suppressing interferon regulatory factor 2.
Pagliari C, Marcoli GM, Kanashiro-Galo L, Mello ES, Carvalho LV, Penny R, Quaresma JS, Vasconcelos PFDC, Sotto MN
Revista do Instituto de Medicina Tropical de Sao Paulo 2026;68:e21
Revista do Instituto de Medicina Tropical de Sao Paulo 2026;68:e21
Histopathological Alterations and Dysregulation of Type I Interferon Signaling in the Human Cerebral Cortex During Severe Dengue.
Castro LM, Fernandes ER, Quaresma JAS, Lancelotti CLP, Duarte MIS, Carvalho LV, Penny R, Vasconcelos PFDC, Mello ES, Sotto MN, Pagliari C
Journal of medical virology 2025 Oct;97(10):e70644
Journal of medical virology 2025 Oct;97(10):e70644
IRF2 Affects LPS- and IFN-γ-Induced Pro-Inflammatory Responses, Cell Viability, Migration and Apoptosis of Macrophages by Regulating IRG1.
Qin RX, Ma XY, Han ZY, Ma SY, Shen ZJ, Lu ZH, Sun Y, Yu WL
Journal of inflammation research 2024;17:9651-9664
Journal of inflammation research 2024;17:9651-9664
Novel hypermorphic variants in IRF2BP2 identified in patients with common variable immunodeficiency and autoimmunity.
Anim M, Sogkas G, Camacho-Ordonez N, Schmidt G, Elsayed A, Proietti M, Witte T, Grimbacher B, Atschekzei F
Clinical immunology (Orlando, Fla.) 2024 Sep;266:110326
Clinical immunology (Orlando, Fla.) 2024 Sep;266:110326
Lnc-PLCB1 is stabilized by METTL14 induced m6A modification and inhibits Helicobacter pylori mediated gastric cancer by destabilizing DDX21.
Chang M, Cui X, Sun Q, Wang Y, Liu J, Sun Z, Ren J, Sun Y, Han L, Li W
Cancer letters 2024 Apr 28;588:216746
Cancer letters 2024 Apr 28;588:216746
Long noncoding RNA SENCR facilitates the progression of acute myeloid leukemia through the miR-4731-5p/IRF2 pathway.
Han C, Qi Y, She Y, Zhang M, Xie H, Zhang J, Zhao Z, Peng C, Liu Y, Lin Y, Wang J, Zeng D
Pathology, research and practice 2023 May;245:154483
Pathology, research and practice 2023 May;245:154483
Analysis of miRNA Expression Profiling of RIP2 Knockdown in Chicken HD11 Cells When Infected with Avian Pathogenic E. coli (APEC).
Sun H, Cao Y, Yang Y, Li H, Qu L
International journal of molecular sciences 2022 Jun 30;23(13)
International journal of molecular sciences 2022 Jun 30;23(13)
IRF2-ferroptosis related gene is associated with prognosis and EMT in gliomas.
Tong S, Ye L, Xu Y, Sun Q, Gao L, Cai J, Ye Z, Tian D, Chen Q
Translational oncology 2022 Dec;26:101544
Translational oncology 2022 Dec;26:101544
Propofol Ameliorates Microglia Activation by Targeting MicroRNA-221/222-IRF2 Axis.
Xiao X, Hou Y, Yu W, Qi S
Journal of immunology research 2021;2021:3101146
Journal of immunology research 2021;2021:3101146
IRF2 inhibits ZIKV replication by promoting FAM111A expression to enhance the host restriction effect of RFC3.
Ren K, Zhu Y, Sun H, Li S, Duan X, Li S, Li Y, Li B, Chen L
Virology journal 2021 Dec 20;18(1):256
Virology journal 2021 Dec 20;18(1):256
MicroRNA-664 functions as an oncogene in cutaneous squamous cell carcinomas (cSCC) via suppressing interferon regulatory factor 2.
Li X, Zhou C, Zhang C, Xie X, Zhou Z, Zhou M, Chen L, Ding Z
Journal of dermatological science 2019 Jun;94(3):330-338
Journal of dermatological science 2019 Jun;94(3):330-338
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 12525-1-AP(IRF2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 12525-1-AP(IRF2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IRF2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IRF2. This antibody recognizes human, mouse, rat antigen. The IRF2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
