HPA023393

antibody from Atlas Antibodies

Targeting: HROB C17orf53, MCM8IP, MGC3130

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA023393

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA023393, RRID:AB_1853878

Product name

Anti-C17orf53

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human C17orf53, Gene description: chromosome 17 open reading frame 53, Alternative Gene Names: MGC3130, Validated applications: WB, IHC, Uniprot ID: Q8N3J3, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Mechanism of DNA unwinding by MCM8-9 in complex with HROB

Acharya A, Bret H, Huang J, Mütze M, Göse M, Kissling V, Seidel R, Ciccia A, Guérois R, Cejka P
Nature Communications 2024;15(1)

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Acharya A, Bret H, Huang J, Muetze M, Goese M, Kissling V, Seidel R, Ciccia A, Guérois R, Cejka P
2023

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TERRA transcription destabilizes telomere integrity to initiate break-induced replication in human ALT cells.

Silva B, Arora R, Bione S, Azzalin CM
Nature communications 2021 Jun 18;12(1):3760

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C17orf53 is identified as a novel gene involved in inter-strand crosslink repair

Wang C, Chen Z, Su D, Tang M, Nie L, Zhang H, Feng X, Wang R, Shen X, Srivastava M, McLaughlin M, Hart T, Li L, Chen J
DNA Repair 2020;95

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MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage

Huang J, Acharya A, Taglialatela A, Nambiar T, Cuella-Martin R, Leuzzi G, Hayward S, Joseph S, Brunette G, Anand R, Soni R, Clark N, Bernstein K, Cejka P, Ciccia A
Nature Communications 2020;11(1)