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- References [20]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 23306-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#23306-1-AP, RRID:AB_2721185
- Product name
- WWTR1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated WWTR1 antibody (Cat. #23306-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Traditional Chinese medicine Yiqi Huoxue recipe attenuates hepatic fibrosis via YAP/TAZ signaling.
YAP drives fate conversion and chemoresistance of small cell lung cancer.
CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells.
TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling.
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
YAP and TAZ regulate Schwann cell proliferation and differentiation during peripheral nerve regeneration.
The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro.
MiR-34a-5p Inhibits Proliferation, Migration, Invasion and Epithelial-mesenchymal Transition in Esophageal Squamous Cell Carcinoma by Targeting LEF1 and Inactivation of the Hippo-YAP1/TAZ Signaling Pathway.
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.
A Division of Labor between YAP and TAZ in Non-Small Cell Lung Cancer.
Eva-1 homolog A promotes papillary thyroid cancer progression and epithelial-mesenchymal transition via the Hippo signalling pathway.
Vitamin D3 analogue facilitates epithelial wound healing through promoting epithelial-mesenchymal transition via the Hippo pathway.
TRIB3 confers radiotherapy resistance in esophageal squamous cell carcinoma by stabilizing TAZ.
Jiedu Sangen Decoction Inhibits the Invasion and Metastasis of Colorectal Cancer Cells by Regulating EMT through the Hippo Signaling Pathway.
miR-125 inhibits colorectal cancer proliferation and invasion by targeting TAZ.
MicroRNA-144 inhibits proliferation by targeting WW domain-containing transcription regulator protein 1 in papillary thyroid cancer.
Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis.
YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells.
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Zhao W, Zhang X, Hou M, Zhang Y, Tang Y, Li L, Dong S, Liu L, Zhao D, Li W, Nan Y
Histology and histopathology 2021 Sep;36(9):967-979
Histology and histopathology 2021 Sep;36(9):967-979
YAP drives fate conversion and chemoresistance of small cell lung cancer.
Wu Q, Guo J, Liu Y, Zheng Q, Li X, Wu C, Fang D, Chen X, Ma L, Xu P, Xu X, Liao C, Wu M, Shen L, Song H
Science advances 2021 Oct;7(40):eabg1850
Science advances 2021 Oct;7(40):eabg1850
CSE1L promotes nuclear accumulation of transcriptional coactivator TAZ and enhances invasiveness of human cancer cells.
Nagashima S, Maruyama J, Honda K, Kondoh Y, Osada H, Nawa M, Nakahama KI, Ishigami-Yuasa M, Kagechika H, Sugimura H, Iwasa H, Arimoto-Matsuzaki K, Nishina H, Hata Y
The Journal of biological chemistry 2021 Jul;297(1):100803
The Journal of biological chemistry 2021 Jul;297(1):100803
TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling.
Yang W, Lu X, Zhang T, Han W, Li J, He W, Jia Y, Zhao K, Qin A, Qian Y
Bone research 2021 Jul 12;9(1):33
Bone research 2021 Jul 12;9(1):33
Rosmarinic acid exerts an antagonistic effect on nonalcoholic fatty liver disease by regulating the YAP1/TAZ-PPARγ/PGC-1α signaling pathway.
Luo C, Sun H, Peng J, Gao C, Bao L, Ji R, Zhang C, Zhu W, Jin Y
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
Phytotherapy research : PTR 2021 Feb;35(2):1010-1022
The RNA binding protein QKI5 suppresses ovarian cancer via downregulating transcriptional coactivator TAZ.
Liu T, Yang Y, Xie Z, Luo Q, Yang D, Liu X, Zhao H, Wei Q, Liu Y, Li L, Wang Y, Wang F, Yu J, Xu J, Yu J, Yi P
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
Molecular therapy. Nucleic acids 2021 Dec 3;26:388-400
YAP and TAZ regulate Schwann cell proliferation and differentiation during peripheral nerve regeneration.
Jeanette H, Marziali LN, Bhatia U, Hellman A, Herron J, Kopec AM, Feltri ML, Poitelon Y, Belin S
Glia 2021 Apr;69(4):1061-1074
Glia 2021 Apr;69(4):1061-1074
The lncRNA BCYRN1 Functions as an Oncogene in Human Glioma by Downregulating miR-125a-5p in vitro.
Yu W, Xiang D, Jia H, He X, Sheng J, Long Y, Zhu S, Wang K, Liu Q
Cancer management and research 2020;12:1151-1161
Cancer management and research 2020;12:1151-1161
MiR-34a-5p Inhibits Proliferation, Migration, Invasion and Epithelial-mesenchymal Transition in Esophageal Squamous Cell Carcinoma by Targeting LEF1 and Inactivation of the Hippo-YAP1/TAZ Signaling Pathway.
Wang X, Zhao Y, Lu Q, Fei X, Lu C, Li C, Chen H
Journal of Cancer 2020;11(10):3072-3081
Journal of Cancer 2020;11(10):3072-3081
YTHDF2/3 Are Required for Somatic Reprogramming through Different RNA Deadenylation Pathways.
Liu J, Gao M, Xu S, Chen Y, Wu K, Liu H, Wang J, Yang X, Wang J, Liu W, Bao X, Chen J
Cell reports 2020 Sep 8;32(10):108120
Cell reports 2020 Sep 8;32(10):108120
A Division of Labor between YAP and TAZ in Non-Small Cell Lung Cancer.
Shreberk-Shaked M, Dassa B, Sinha S, Di Agostino S, Azuri I, Mukherjee S, Aylon Y, Blandino G, Ruppin E, Oren M
Cancer research 2020 Oct 1;80(19):4145-4157
Cancer research 2020 Oct 1;80(19):4145-4157
Eva-1 homolog A promotes papillary thyroid cancer progression and epithelial-mesenchymal transition via the Hippo signalling pathway.
Lin BY, Wen JL, Zheng C, Lin LZ, Chen CZ, Qu JM
Journal of cellular and molecular medicine 2020 Nov;24(22):13070-13080
Journal of cellular and molecular medicine 2020 Nov;24(22):13070-13080
Vitamin D3 analogue facilitates epithelial wound healing through promoting epithelial-mesenchymal transition via the Hippo pathway.
Wang D, Lin L, Lei K, Zeng J, Luo J, Yin Y, Li Y, Zhang L, Nie X, Zuo D, Sun L
Journal of dermatological science 2020 Nov;100(2):120-128
Journal of dermatological science 2020 Nov;100(2):120-128
TRIB3 confers radiotherapy resistance in esophageal squamous cell carcinoma by stabilizing TAZ.
Zhou S, Liu S, Lin C, Li Y, Ye L, Wu X, Jian Y, Dai Y, Ouyang Y, Zhao L, Liu M, Song L, Xi M
Oncogene 2020 Apr;39(18):3710-3725
Oncogene 2020 Apr;39(18):3710-3725
Jiedu Sangen Decoction Inhibits the Invasion and Metastasis of Colorectal Cancer Cells by Regulating EMT through the Hippo Signaling Pathway.
Yuan L, Zhou M, Wasan HS, Zhang K, Li Z, Guo K, Shen F, Shen M, Ruan S
Evidence-based complementary and alternative medicine : eCAM 2019;2019:1431726
Evidence-based complementary and alternative medicine : eCAM 2019;2019:1431726
miR-125 inhibits colorectal cancer proliferation and invasion by targeting TAZ.
Yang M, Tang X, Wang Z, Wu X, Tang D, Wang D
Bioscience reports 2019 Dec 20;39(12)
Bioscience reports 2019 Dec 20;39(12)
MicroRNA-144 inhibits proliferation by targeting WW domain-containing transcription regulator protein 1 in papillary thyroid cancer.
Sun W, Lan X, Wang Z, Dong W, He L, Zhang T, Zhang P, Zhang H
Oncology letters 2018 Jan;15(1):1007-1013
Oncology letters 2018 Jan;15(1):1007-1013
Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis.
Wu LMN, Deng Y, Wang J, Zhao C, Wang J, Rao R, Xu L, Zhou W, Choi K, Rizvi TA, Remke M, Rubin JB, Johnson RL, Carroll TJ, Stemmer-Rachamimov AO, Wu J, Zheng Y, Xin M, Ratner N, Lu QR
Cancer cell 2018 Feb 12;33(2):292-308.e7
Cancer cell 2018 Feb 12;33(2):292-308.e7
YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells.
Poitelon Y, Lopez-Anido C, Catignas K, Berti C, Palmisano M, Williamson C, Ameroso D, Abiko K, Hwang Y, Gregorieff A, Wrana JL, Asmani M, Zhao R, Sim FJ, Wrabetz L, Svaren J, Feltri ML
Nature neuroscience 2016 Jul;19(7):879-87
Nature neuroscience 2016 Jul;19(7):879-87
Deacetylation of tumor-suppressor MST1 in Hippo pathway induces its degradation through HBXIP-elevated HDAC6 in promotion of breast cancer growth.
Li L, Fang R, Liu B, Shi H, Wang Y, Zhang W, Zhang X, Ye L
Oncogene 2016 Aug 4;35(31):4048-57
Oncogene 2016 Aug 4;35(31):4048-57
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with 23306-1-AP( WWTR1,TAZ Antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TAZ antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TAZ. This antibody recognizes human antigen. The TAZ antibody has been validated for the following applications: ELISA, WB, IHC analysis.
