HPA017732

CNNM4 antibody from Atlas Antibodies

ACDP4, KIAA1592

Eligible for validation within the Antibodypedia Validation Initiative

Immunohistochemistry

Enhanced validation

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Antibody Data

Product number

HPA017732

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA017732, RRID:AB_1847395

Product name

Anti-CNNM4

Provider product page

Antibody type

Polyclonal

Description

Affinity purified using the PrEST antigen as affinity ligand

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Antigen sequence

FSYYGTMALTSVPSDRSPAHPTPLSRSASLSYPDR
TDVSTAATLAGSSNQFGSSVLGQYISDFSVRALVD
LQYIKITRQQYQNGLLASRMENSPQFPIDGCTTHM
ENLAEKSELPVVDETTTLLNERNSL


Isotype

IgG

Vial size

100 µl

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

References

Mutations in CNNM4 Cause Jalili Syndrome, Consisting of Autosomal-Recessive Cone-Rod Dystrophy and Amelogenesis Imperfecta
Parry D, Mighell A, El-Sayed W, Shore R, Jalili I, Dollfus H, Bloch-Zupan A, Carlos R, Carr I, Downey L, Blain K, Mansfield D, Shahrabi M, Heidari M, Aref P, Abbasi M, Michaelides M, Moore A, Kirkham J, Inglehearn C
The American Journal of Human Genetics 2009 February;84(2):266-273

Immunohistochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human appendix shows cytoplasmic and membranous positivity in glandular cells.

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human rectum shows high expression.

Sample type

HUMAN

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of human pancreas shows low expression as expected.

Sample type

HUMAN

Enhanced validation

Submitted by

Atlas Antibodies (provider)

Enhanced method

Orthogonal validation

Main image

Experimental details

Immunohistochemistry analysis in human rectum and pancreas tissues using Anti-CNNM4 antibody. Corresponding CNNM4 RNA-seq data are presented for the same tissues.

Sample type

HUMAN

Orthogonal method

Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

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