orb2634791

antibody from Biorbyt
Targeting: ZNF276 CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477
Provider product page for orb2634791
ELISA
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb2634791 - Provider product page
Provider
Biorbyt
Product name
ZNF276 Antibody
Antibody type
Monoclonal
Description
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PCRP-ZNF276-1A5
Vial size
20 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ZNF276 protein structure - orb2634791 shown in red.