619002

antibody from BioLegend

Targeting: TP63 EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L

Immunocytochemistry

Antibody data

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Validation data

Product number: 619002 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#619002, RRID:AB_2207170
Product name: Purified anti-p63 (N)
Antibody type: Polyclonal
Antigen: Modified peptide
Description: p63 (ΔN) is a member of the p53 family. This protein has multiple isoforms TA p63-α, -β, γ, ΔN p63-α, -β, and -γ. The molecular weights of the p63 isoforms α=66 kD, β=52 kD, and γ=45 kD. This nuclear protein is essential for limb formation, epidermal morphogenesis, and epithelial stem cell regeneration. ΔN isoforms are antagonistic to p53; TA isoforms can transactivate p53 targets. The p63 ΔN isoforms repress TA isoforms; mutant p53 abrogates p63 transactivation. This protein interacts with p53, p73, and the various TA- and ΔN isoforms. The Poly6190 antibody recognizes human p63 ΔN isoforms and has been shown to be useful for Western blotting.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Vial size: 200 µl
Storage: Upon receipt, store frozen at -20° C.

TP63 protein structure - 619002 shown in red.