Ab119899

antibody from Aladdin Scientific

Targeting: TP63 EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L

Antibody data

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Validation data

Product number: Ab119899 - Provider product page
Provider: Aladdin Scientific
Product name: p63 Mouse mAb
Antibody type: Monoclonal
Description: Mouse anti Human p63 Antibody, Monoclonal (D2), could be used for WB and so on.Application:WB: 0.01-2 µg/mLProtein FunctionActs as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge.
Reactivity: Human, Porcine
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: AA 540~680
Antibody clone number: D2
Vial size: 100_l,10_l,1ml,20_l,50_l
Concentration: Lot by Lot
Storage: Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

TP63 protein structure - Ab119899 shown in red.