ABIN93814

antibody from antibodies-online

Targeting: TP63 EEC3, KET, NBP, OFC8, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN93814

Provider

antibodies-online

Product name

anti-Tumor Protein P63 (TP63) antibody

Antibody type

Monoclonal

Antigen

Recombinant p63 Protein (AA 1-205) N-terminal part of deltaNp63

Reactivity

Human, Mouse, Rat

Host

Mouse

Isotype

IgG

Antibody clone number

4A4

Vial size

5 mL

Storage

4°C

References

Submitted references

p63 immunoreactivity in lung cancer: yet another player in the development of squamous cell carcinomas?

Pelosi G, Pasini F, Olsen Stenholm C, Pastorino U, Maisonneuve P, Sonzogni A, Maffini F, Pruneri G, Fraggetta F, Cavallon A, Roz E, Iannucci A, Bresaola E, Viale G
The Journal of pathology 2002 Sep;198(1):100-9

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p63 is a prostate basal cell marker and is required for prostate development.

Signoretti S, Waltregny D, Dilks J, Isaac B, Lin D, Garraway L, Yang A, Montironi R, McKeon F, Loda M
The American journal of pathology 2000 Dec;157(6):1769-75

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Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome.

Celli J, Duijf P, Hamel BC, Bamshad M, Kramer B, Smits AP, Newbury-Ecob R, Hennekam RC, Van Buggenhout G, van Haeringen A, Woods CG, van Essen AJ, de Waal R, Vriend G, Haber DA, Yang A, McKeon F, Brunner HG, van Bokhoven H
Cell 1999 Oct 15;99(2):143-53

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p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities.

Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dötsch V, Andrews NC, Caput D, McKeon F
Molecular cell 1998 Sep;2(3):305-16