Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS6749 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- TLR3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human TLR3.
- Description
- Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated Toll-like receptors (TLR). TLR3 is highly expressed in placenta and pancreas, and is limited to the dendritic subpopulation of leukocytes. TLR3 recognizes dsRNA associated with viral infection and induces activation of NFkB and production of type I interferons, which suggests that it may play a role in host defense against viruses. TLR6 is highly homologous to TLR1, sharing greater than 65% sequence identity. Like other members of TLR family, TLR6 induces NFkB signaling upon activation.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot analysis of extracts from Molt-4 cell, using TLR3 antibody.