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Western blot
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ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunocytochemistry [2]
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- Product number
- ALX-804-362-C100 - Provider product page
- Provider
- Enzo Life Sciences
- Product name
- Toll-like receptor 3 monoclonal antibody (40C1285.6)
- Antibody type
- Monoclonal
- Antigen
- Synthetic peptide
- Description
- Protein G-affinity purified.
- Reactivity
- Human, Mouse, Canine
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 40C1285.6
- Vial size
- 100 μg
- Storage
- -20°C
- Handling
- Avoid freeze/thaw cycles.
Submitted references Biochemical and functional analyses of the human Toll-like receptor 3 ectodomain.
Effects of single nucleotide polymorphisms on Toll-like receptor 3 activity and expression in cultured cells.
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.
Regulation of the polymeric Ig receptor by signaling through TLRs 3 and 4: linking innate and adaptive immune responses.
Toll-like receptors-2, -3 and -4 expression patterns on human colon and their regulation by mucosal-associated bacteria.
Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes.
The effect of innate immunity on autoimmune diabetes and the expression of Toll-like receptors on pancreatic islets.
Subcellular localization of Toll-like receptor 3 in human dendritic cells.
Ranjith-Kumar CT, Miller W, Xiong J, Russell WK, Lamb R, Santos J, Duffy KE, Cleveland L, Park M, Bhardwaj K, Wu Z, Russell DH, Sarisky RT, Mbow ML, Kao CC
The Journal of biological chemistry 2007 Mar 9;282(10):7668-78
The Journal of biological chemistry 2007 Mar 9;282(10):7668-78
Effects of single nucleotide polymorphisms on Toll-like receptor 3 activity and expression in cultured cells.
Ranjith-Kumar CT, Miller W, Sun J, Xiong J, Santos J, Yarbrough I, Lamb RJ, Mills J, Duffy KE, Hoose S, Cunningham M, Holzenburg A, Mbow ML, Sarisky RT, Kao CC
The Journal of biological chemistry 2007 Jun 15;282(24):17696-705
The Journal of biological chemistry 2007 Jun 15;282(24):17696-705
Intracellular signaling mechanisms regulating toll-like receptor-mediated activation of eosinophils.
Wong CK, Cheung PF, Ip WK, Lam CW
American journal of respiratory cell and molecular biology 2007 Jul;37(1):85-96
American journal of respiratory cell and molecular biology 2007 Jul;37(1):85-96
Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.
Harii N, Lewis CJ, Vasko V, McCall K, Benavides-Peralta U, Sun X, Ringel MD, Saji M, Giuliani C, Napolitano G, Goetz DJ, Kohn LD
Molecular endocrinology (Baltimore, Md.) 2005 May;19(5):1231-50
Molecular endocrinology (Baltimore, Md.) 2005 May;19(5):1231-50
Regulation of the polymeric Ig receptor by signaling through TLRs 3 and 4: linking innate and adaptive immune responses.
Schneeman TA, Bruno ME, Schjerven H, Johansen FE, Chady L, Kaetzel CS
Journal of immunology (Baltimore, Md. : 1950) 2005 Jul 1;175(1):376-84
Journal of immunology (Baltimore, Md. : 1950) 2005 Jul 1;175(1):376-84
Toll-like receptors-2, -3 and -4 expression patterns on human colon and their regulation by mucosal-associated bacteria.
Furrie E, Macfarlane S, Thomson G, Macfarlane GT, Microbiology & Gut Biology Group, Tayside Tissue & Tumour Bank
Immunology 2005 Aug;115(4):565-74
Immunology 2005 Aug;115(4):565-74
Distinct poly(I-C) and virus-activated signaling pathways leading to interferon-beta production in hepatocytes.
Li K, Chen Z, Kato N, Gale M Jr, Lemon SM
The Journal of biological chemistry 2005 Apr 29;280(17):16739-47
The Journal of biological chemistry 2005 Apr 29;280(17):16739-47
The effect of innate immunity on autoimmune diabetes and the expression of Toll-like receptors on pancreatic islets.
Wen L, Peng J, Li Z, Wong FS
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 1;172(5):3173-80
Journal of immunology (Baltimore, Md. : 1950) 2004 Mar 1;172(5):3173-80
Subcellular localization of Toll-like receptor 3 in human dendritic cells.
Matsumoto M, Funami K, Tanabe M, Oshiumi H, Shingai M, Seto Y, Yamamoto A, Seya T
Journal of immunology (Baltimore, Md. : 1950) 2003 Sep 15;171(6):3154-62
Journal of immunology (Baltimore, Md. : 1950) 2003 Sep 15;171(6):3154-62
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Supportive validation
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Western blot analysis of TLR3 in lysates from untransfected 293 cells (lane A), 293 cells transfected with human TLR3 cDNA (lane B), and 20µg/lane human intestine tissue lysate (lane C).
- Submitted by
- Enzo Life Sciences (provider)
- Main image
- Experimental details
- Immunohistochemistry of human gut lumen (longitudinal section, transverse region) using MAb to Toll-like Receptor 3 (human) (40C1285.6) (Prod. No. ALX-804-362) at 10µg/ml. Data courtesy Dr. Elizabeth Furrie, University of Dundee.
