Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AF1487 - Provider product page
- Provider
- R&D Systems
- Product name
- Human TLR3 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human TLR3 in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
O15455
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Increased expression of toll-like receptor 3, an anti-viral signaling molecule, and related genes in Alzheimer's disease brains.
Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness.
Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5.
Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization.
LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs.
Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.
Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity.
Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cells.
Activation of Toll-like receptor 3 augments myofibroblast differentiation.
Walker DG, Tang TM, Lue LF
Experimental neurology 2018 Nov;309:91-106
Experimental neurology 2018 Nov;309:91-106
Surface Toll-like receptor 3 expression in metastatic intestinal epithelial cells induces inflammatory cytokine production and promotes invasiveness.
Bugge M, Bergstrom B, Eide OK, Solli H, Kjønstad IF, Stenvik J, Espevik T, Nilsen NJ
The Journal of biological chemistry 2017 Sep 15;292(37):15408-15425
The Journal of biological chemistry 2017 Sep 15;292(37):15408-15425
Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5.
Huang LY, Stuart C, Takeda K, D'Agnillo F, Golding B
PloS one 2016;11(8):e0160875
PloS one 2016;11(8):e0160875
Proteolytic processing regulates Toll-like receptor 3 stability and endosomal localization.
Qi R, Singh D, Kao CC
The Journal of biological chemistry 2012 Sep 21;287(39):32617-29
The Journal of biological chemistry 2012 Sep 21;287(39):32617-29
LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs.
Lai Y, Adhikarakunnathu S, Bhardwaj K, Ranjith-Kumar CT, Wen Y, Jordan JL, Wu LH, Dragnea B, San Mateo L, Kao CC
PloS one 2011;6(10):e26632
PloS one 2011;6(10):e26632
Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.
Lai Y, Yi G, Chen A, Bhardwaj K, Tragesser BJ, Rodrigo A Valverde, Zlotnick A, Mukhopadhyay S, Ranjith-Kumar CT, Kao CC
PloS one 2011;6(10):e25837
PloS one 2011;6(10):e25837
Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity.
Guo Y, Audry M, Ciancanelli M, Alsina L, Azevedo J, Herman M, Anguiano E, Sancho-Shimizu V, Lorenzo L, Pauwels E, Philippe PB, Pérez de Diego R, Cardon A, Vogt G, Picard C, Andrianirina ZZ, Rozenberg F, Lebon P, Plancoulaine S, Tardieu M, Valérie Doireau, Jouanguy E, Chaussabel D, Geissmann F, Abel L, Casanova JL, Zhang SY
The Journal of experimental medicine 2011 Sep 26;208(10):2083-98
The Journal of experimental medicine 2011 Sep 26;208(10):2083-98
Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cells.
Koarai A, Sugiura H, Yanagisawa S, Ichikawa T, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Ichinose M
American journal of respiratory cell and molecular biology 2010 Jun;42(6):651-60
American journal of respiratory cell and molecular biology 2010 Jun;42(6):651-60
Activation of Toll-like receptor 3 augments myofibroblast differentiation.
Sugiura H, Ichikawa T, Koarai A, Yanagisawa S, Minakata Y, Matsunaga K, Hirano T, Akamatsu K, Ichinose M
American journal of respiratory cell and molecular biology 2009 Jun;40(6):654-62
American journal of respiratory cell and molecular biology 2009 Jun;40(6):654-62
No comments: Submit comment
No validations: Submit validation data