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- References [17]
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- Product number
- 24272-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Frizzled 2 antibody
- Antibody type
- Polyclonal
- Description
- Frizzled 2 antibody (Cat. #24272-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references MBD2 promotes epithelial-to-mesenchymal transition (EMT) and ARDS-related pulmonary fibrosis by modulating FZD2.
Gen inhibiting the Wnt/Ca(2+) signaling pathway alleviates cerebral ischemia/reperfusion injury.
Bioinspired nanoparticles prevent blue-light-induced skin hyperpigmentation via FZD2-TYR-melanin pathway.
CD44 is a macrophage receptor for TcdB from Clostridioides difficile that via its lysine-158 succinylation contributes to inflammation.
ZNF831-YTHDF1-DNMT1/3a feedback loop regulates lung carcinogenesis and progression through WNT7B-FZD5-β-catenin signalling axis.
M1-BMDMs with Wnt5a deletion attenuate liver fibrosis by suppression of Wnt5a/Frizzled 2 axis in hepatic progenitors.
Interference of FZD2 suppresses proliferation, vasculogenic mimicry and stemness in glioma cells via blocking the Notch/NF‑κB signaling pathway.
The oncogenic role and regulatory mechanism of ACAA2 in human ovarian cancer.
Exosomal miR-320e through wnt2targeted inhibition of the Wnt/β-catenin pathway allevisate cerebral small vessel disease and cognitive impairment.
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model.
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Depletion of VPS35 attenuates metastasis of hepatocellular carcinoma by restraining the Wnt/PCP signaling pathway.
Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer.
Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.
Expression and (Lacking) Internalization of the Cell Surface Receptors of Clostridioides difficile Toxin B.
Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia.
Zhou Y, Yang G, Liu J, Yao S, Jia J, Tang X, Gong X, Wan F, Wu R, Zhao Z, Liang H, Liu L, Liu Q, Xie S, Long X, Xiang X, Wang G, Xiao B
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167798
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167798
Gen inhibiting the Wnt/Ca(2+) signaling pathway alleviates cerebral ischemia/reperfusion injury.
Li L, Liu S, Wang M, Li M, Liu Y, Chen H, Chen J, Tao W, Huang L, Zhao S
Scientific reports 2025 Feb 7;15(1):4661
Scientific reports 2025 Feb 7;15(1):4661
Bioinspired nanoparticles prevent blue-light-induced skin hyperpigmentation via FZD2-TYR-melanin pathway.
Chen X, Wu T, Chen Z, Zhang J, Zhou Y, Wang Q, Wang B, Wang Z, Jin X, Xiong S, Zhang T, Gao S, Ma J, Deng Z, Chen X, Li C, Jian Z
Materials today. Bio 2025 Dec;35:102288
Materials today. Bio 2025 Dec;35:102288
CD44 is a macrophage receptor for TcdB from Clostridioides difficile that via its lysine-158 succinylation contributes to inflammation.
Chen Z, Zhang W, Wang D, Luo R, Yao Y, Tao X, Li L, Pan Q, Sun X
Gut microbes 2025 Dec;17(1):2506192
Gut microbes 2025 Dec;17(1):2506192
ZNF831-YTHDF1-DNMT1/3a feedback loop regulates lung carcinogenesis and progression through WNT7B-FZD5-β-catenin signalling axis.
Chen D, Chen H, Zeng Y, Shi Y, Guo F, Fan J, Zhang Z, Zhou S, Wang N, Deng S, Liu J, Cao J, Liu W
Free radical biology & medicine 2025 Dec 16;241:338-352
Free radical biology & medicine 2025 Dec 16;241:338-352
M1-BMDMs with Wnt5a deletion attenuate liver fibrosis by suppression of Wnt5a/Frizzled 2 axis in hepatic progenitors.
Xing FF, Wang DY, Xu YN, Zheng XR, Zhang SH, Zong MY, Zhan JY, Wang DX, Liu W, Chen JM, Chen GF, Liu P, Liu CH, Mu YP
Cell & bioscience 2025 Aug 30;15(1):125
Cell & bioscience 2025 Aug 30;15(1):125
Interference of FZD2 suppresses proliferation, vasculogenic mimicry and stemness in glioma cells via blocking the Notch/NF‑κB signaling pathway.
Ran Y, Han S, Gao D, Chen X, Liu C
Experimental and therapeutic medicine 2024 Oct;28(4):373
Experimental and therapeutic medicine 2024 Oct;28(4):373
The oncogenic role and regulatory mechanism of ACAA2 in human ovarian cancer.
Leng Y, Tian T, Tang B, Ma Y, Li Z, Shi Q, Liu J, Zhou Y, Wang W, Huang C, Zhao X, Feng W, Liu Y, Liang J, Liu T, Liu S, Ren Q, Liu J, Zhang T, Zhou J, Huang Q, Zhang Y, Yin B, Xu Y, Liu L, Shen L, Zhao H
Molecular carcinogenesis 2024 Jul;63(7):1362-1377
Molecular carcinogenesis 2024 Jul;63(7):1362-1377
Exosomal miR-320e through wnt2targeted inhibition of the Wnt/β-catenin pathway allevisate cerebral small vessel disease and cognitive impairment.
Wang Z, Li XN, Yang SN, Wang Y, Gao KJ, Han B, Ma AJ
World journal of psychiatry 2023 Sep 19;13(9):630-644
World journal of psychiatry 2023 Sep 19;13(9):630-644
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling.
Wu H, Tang LX, Wang XM, Li LP, Chen XK, He YJ, Yang DZ, Shi Y, Shou JL, Zhang ZS, Wang L, Lu BJ, An SM, Zeng CY, Wang WE
Acta pharmacologica Sinica 2023 Jun;44(6):1149-1160
Acta pharmacologica Sinica 2023 Jun;44(6):1149-1160
Electroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model.
Ding Y, Li L, Wang S, Cao Y, Yang M, Dai Y, Lin H, Li J, Liu Y, Wang Z, Liu W, Tao J
Biological research 2023 Dec 2;56(1):65
Biological research 2023 Dec 2;56(1):65
Intervention Mechanism of Hunag-Lian Jie-Du Decoction on Canonical Wnt/β-Catenin Signaling Pathway in Psoriasis Mouse Model.
Yang X, Luo G, Fu L, Huang H, Wang L, Yin L, Zhang X, Wang T, Ma X, Feng T, Ye J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Evidence-based complementary and alternative medicine : eCAM 2022;2022:3193572
Depletion of VPS35 attenuates metastasis of hepatocellular carcinoma by restraining the Wnt/PCP signaling pathway.
Liu Y, Deng H, Liang L, Zhang G, Xia J, Ding K, Tang N, Wang K
Genes & diseases 2021 Mar;8(2):232-240
Genes & diseases 2021 Mar;8(2):232-240
Cholesterol activates the Wnt/PCP-YAP signaling in SOAT1-targeted treatment of colon cancer.
Xu H, Xia H, Zhou S, Tang Q, Bi F
Cell death discovery 2021 Feb 26;7(1):38
Cell death discovery 2021 Feb 26;7(1):38
Yiguanjian decoction inhibits macrophage M1 polarization and attenuates hepatic fibrosis induced by CCl(4)/2-AAF.
Xu Y, Xu W, Liu W, Chen G, Jiang S, Chen J, Jian X, Zhang H, Liu P, Mu Y
Pharmaceutical biology 2021 Dec;59(1):1150-1160
Pharmaceutical biology 2021 Dec;59(1):1150-1160
Expression and (Lacking) Internalization of the Cell Surface Receptors of Clostridioides difficile Toxin B.
Schöttelndreier D, Seeger K, Grassl GA, Winny MR, Lindner R, Genth H
Frontiers in microbiology 2018;9:1483
Frontiers in microbiology 2018;9:1483
Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia.
Liu W, Zhang L, Xuan K, Hu C, Li L, Zhang Y, Jin F, Jin Y
Theranostics 2018;8(20):5575-5592
Theranostics 2018;8(20):5575-5592
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Frizzled 2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Frizzled 2. This antibody recognizes human, mouse, rat antigen. The Frizzled 2 antibody has been validated for the following applications: ELISA, WB analysis.
