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- Antigen structure
- References [89]
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- Product number
- 67381-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- TSG101 antibody
- Antibody type
- Monoclonal
- Description
- TSG101 antibody (Cat. #67381-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: FC, IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2B7G8
- Vial size
- 20ul, 150ul
Submitted references Extracellular vesicles-derived hybrid biomimetic nanoplatforms camouflaged Golgi apparatus-targeted aggregation induced emission photosensitizer to elicit pyroptosis and immunogenic cell death for efficient antitumor photoimmunotherapy.
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Exosomal miRNA-218-5p derived from low-passage dermal papilla cells modulates hair follicle growth and development.
Caveolin-1 drives immunosuppression in esophageal squamous cell carcinoma by enhancing exosome secretion and macrophage M2 polarization via inhibition of MVB autophagic degradation.
Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
MiR-93-5p Loaded Lipid Nanoparticles Break the Dry Eye Vicious Cycle via Targeting MAP3K8.
An Integrated Nanozyme-Exosome Platform for Multi-Targeted Therapy of Metabolic-Associated Steatotic Liver Disease.
Exosomal miR-17 Drives Thyroid Cancer Lung Metastasis via NF-κB Activation.
Extracellular Vesicles Derived from FGF2-Primed Astrocytes Against Mitochondrial and Synaptic Toxicities in Parkinson's Disease.
Safety, Efficacy and Bio-Distribution Analysis of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells for Effective Treatment of Bronchopulmonary Dysplasia by Intranasal Administration in Mice Model.
A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosphorylated PKM2-loaded small extracellular vesicles.
Injectable exosome-reinforced konjac glucomannan composite hydrogel for repairing cartilage defect: activation of endogenous antioxidant pathways.
STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.
AntagomiR-192-5p-engineered exosomes encapsulated in MXene-modified GelMA hydrogel facilitated epithelization of burn wounds by targeting OLFM4.
Cancer Cell-Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA.
GENRISE-induced superior extracellular vesicles for scalable therapeutic cargo delivery.
Microneedles combining delivery of hUMSC-derived exosomes and EGCG mitigate UV-induced skin damage.
Exosomal lncRNA MIR210HG derived from hypoxic TAMs promotes the metastasis of triple negative breast cancer.
Histone lactylation-induced GLI3 activation drives macrophage M1 polarization and exosomal SERPINE1 release in abdominal aortic aneurysm progression.
Choline Phosphate Surface-Activated 3D-Printed Porous Titanium Scaffold Combined with Stem Cell Exosomes for Enhancing Bone Defects Repair.
Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia.
Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis.
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Bone marrow mesenchymal stem cell exosomes improve fracture union via remodeling metabolism in nonunion rat model.
Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA.
A Dual-Factor Scaffold for Spinal Cord Injury Repair Targeting Inflammation and Ferroptosis.
Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.
Transdermal psoriasis treatment inspired by tumor microenvironment-mediated immunomodulation and advanced by exosomal engineering.
Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study.
(124)I-labelled BMSC-Derived Extracellular Vesicles Deliver CRISPR/Cas9 Ribonucleoproteins With a GFP-Reporter System to Inhibit Osteosarcoma Proliferation and Metastasis.
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.
Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death.
Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology.
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
Identifying plasma exosome antigens as a potential diagnostic biomarker for tuberculosis disease.
Hypoxia-Challenged Pancreatic Adenocarcinoma Cell-Derived Exosomal circR3HCC1L Drives Tumor Growth Via Upregulating PKM2 Through Sequestering miR-873-5p.
The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer.
Engineered BMSC-derived exosomes deliver miR-17-5p inhibitor to restore sensory conduction via the IL-11/GP130/STAT3/GAP-43 axis in dorsal column lesion.
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections.
Exosomal miR-223-3p from mesenchymal stem cells targets FBXW7 to inhibit intervertebral disc degeneration: mechanism insights.
Vascular Smooth Muscle-Secreted Exosomal X26nt Impedes Atherosclerosis Progression via the c-FOS/XBP1/SOD1 Axis.
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma.
Blockade of Exosome Release Sensitizes Breast Cancer to Doxorubicin via Inhibiting Angiogenesis.
LAMTOR1 decreased exosomal PD-L1 to enhance immunotherapy efficacy in non-small cell lung cancer.
Functional exosomes modified with chitosan effectively alleviate anthracycline-induced cardiotoxicity.
Plasma-derived exosome miR-10a-5p promotes premature ovarian failure by target BDNF via the TrkB/Akt/mTOR signaling pathway.
Research on the role of exosomes secreted by immortalized adipose-derived mesenchymal stem cells differentiated into pericytes in the repair of high glucose-induced retinal vascular endothelial cell damage.
Disease-derived circulating extracellular vesicle preconditioning: A promising strategy for precision mesenchymal stem cell therapy.
Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional properties.
Circulating extracellular vesicles from severe COVID-19 patients induce lung inflammation.
Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms.
Exosomes From IgE-Stimulated Mast Cells Aggravate Asthma-Mediated Atherosclerosis Through circRNA CDR1as-Mediated Endothelial Cell Dysfunction in Mice.
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
Extracellular vesicles from human urine-derived stem cells delay aging through the transfer of PLAU and TIMP1.
Blood-based CNS regionally and neuronally enriched extracellular vesicles carrying pTau217 for Alzheimer's disease diagnosis and differential diagnosis.
Calmodulin-like 5 promotes PEDV replication by regulating late-endosome synthesis and innate immune response.
Bone marrow-fibroblast progenitor cell-derived small extracellular vesicles promote cardiac fibrosis via miR-21-5p and integrin subunit αV signalling.
AS1411 binds to nucleolin via its parallel structure and disrupts the exos-miRNA-27a-mediated reciprocal activation loop between glioma and astrocytes.
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells.
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Exosomes from adipose-derived stem cells overexpressing microRNA-671-3p promote fat graft angiogenesis and adipogenic differentiation.
Subcellular localization of viral proteins after porcine epidemic diarrhea virus infection and their roles in the viral life cycle.
3D-hUMSCs Exosomes Ameliorate Vitiligo by Simultaneously Potentiating Treg Cells-Mediated Immunosuppression and Suppressing Oxidative Stress-Induced Melanocyte Damage.
Targeted treatment of rat AKI induced by rhabdomyolysis using BMSC derived magnetic exosomes and its mechanism.
Locally delivered hydrogels with controlled release of nanoscale exosomes promote cardiac repair after myocardial infarction.
Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.
Dysregulation of MicroRNAs Derived from Plasma Extracellular Vesicles in Schizoaffective Disorder.
Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy.
Engineered Microparticles for Treatment of Murine Brain Metastasis by Reprograming Tumor Microenvironment and Inhibiting MAPK Pathway.
Exosomal ZEB1 Derived from Neural Stem Cells Reduces Inflammation Injury in OGD/R-Treated Microglia via the GPR30-TLR4-NF-κB Axis.
Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non-small cell lung carcinoma.
Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1.
A method for extraction of exosomes from breast tumour cells and characterisation by transmission electron microscopy.
Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis.
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.
Adipose-Derived Circulating Exosomes Promote Protection of the Pulmonary Endothelial Barrier by Inhibiting EndMT and Oxidative Stress through Down-Regulation of the TGF-β Pathway: A Potential Explanation for the Obesity Paradox in ARDS.
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1.
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
Safety and biodistribution of exosomes derived from human induced pluripotent stem cells.
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway.
Construction and analysis of expression profile of exosomal lncRNAs in pleural effusion in lung adenocarcinoma.
Proteomics Analysis of Exosomes From Patients With Active Tuberculosis Reveals Infection Profiles and Potential Biomarkers.
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway.
Zhao X, Wu X, Shang R, Dou H, Chen H, Tan N
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1696-1716
Acta pharmaceutica Sinica. B 2026 Mar;16(3):1696-1716
Early Radial Extracorporeal Shockwave Stimulation on Proximal Tibial Circular Osteotomy Site Enhanced Heterotopic Skin Wound Healing via Small Extracellular Vesicles.
Xie X, Bi S, Su B, Zhou R, Li X, Yan Z, Zhou X, Wang F, Yu T
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Mar;13(16):e17257
Exosomal miRNA-218-5p derived from low-passage dermal papilla cells modulates hair follicle growth and development.
Zhao B, Cai J, Wang M, Li J, Yao S, Bao Z, Chen Y, Wu X
Non-coding RNA research 2026 Jun;18:1-11
Non-coding RNA research 2026 Jun;18:1-11
Caveolin-1 drives immunosuppression in esophageal squamous cell carcinoma by enhancing exosome secretion and macrophage M2 polarization via inhibition of MVB autophagic degradation.
Zhai KR, Zhao PL, Wang ZH, Feng HM, Li ZQ, Huang HR, Yang N, Su ZP, Cui BQ, Song TN, Li B
Journal of translational medicine 2026 Feb 4;24(1)
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Hypoxia-preconditioned cardiomyocyte-derived extracellular vesicles alleviate myocardial ischemic injury by reprogramming macrophage polarization via the Fgl2/NF-κB pathway.
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International immunopharmacology 2026 Feb 1;170:116077
International immunopharmacology 2026 Feb 1;170:116077
MiR-93-5p Loaded Lipid Nanoparticles Break the Dry Eye Vicious Cycle via Targeting MAP3K8.
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ACS applied materials & interfaces 2026 Apr 8;18(13):18740-18754
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Advanced healthcare materials 2026 Apr 12;:e71147
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Exosomal miR-17 Drives Thyroid Cancer Lung Metastasis via NF-κB Activation.
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Extracellular Vesicles Derived from FGF2-Primed Astrocytes Against Mitochondrial and Synaptic Toxicities in Parkinson's Disease.
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International journal of nanomedicine 2025;20:4627-4644
International journal of nanomedicine 2025;20:4627-4644
Safety, Efficacy and Bio-Distribution Analysis of Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells for Effective Treatment of Bronchopulmonary Dysplasia by Intranasal Administration in Mice Model.
Xu W, Jieda X, Wu Y, Du F, Ma L, Luo L, Liu D, Guo L, Liu J, Dong W
International journal of nanomedicine 2025;20:2521-2553
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A novel pathway for stemness propagation and chemoresistance in non-small cell lung cancer via phosphorylated PKM2-loaded small extracellular vesicles.
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Injectable exosome-reinforced konjac glucomannan composite hydrogel for repairing cartilage defect: activation of endogenous antioxidant pathways.
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STING inhibits LINE-1 retrotransposition through sorting ORF1p to lysosomes for degradation.
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EMBO reports 2025 Sep;26(18):4607-4630
EMBO reports 2025 Sep;26(18):4607-4630
AntagomiR-192-5p-engineered exosomes encapsulated in MXene-modified GelMA hydrogel facilitated epithelization of burn wounds by targeting OLFM4.
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Bioactive materials 2025 Oct;52:318-337
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Cancer Cell-Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA.
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GENRISE-induced superior extracellular vesicles for scalable therapeutic cargo delivery.
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Science advances 2025 Oct 24;11(43):eady9680
Science advances 2025 Oct 24;11(43):eady9680
Microneedles combining delivery of hUMSC-derived exosomes and EGCG mitigate UV-induced skin damage.
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Journal of nanobiotechnology 2025 Oct 10;23(1):643
Journal of nanobiotechnology 2025 Oct 10;23(1):643
Exosomal lncRNA MIR210HG derived from hypoxic TAMs promotes the metastasis of triple negative breast cancer.
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International immunopharmacology 2025 Nov 14;165:115416
International immunopharmacology 2025 Nov 14;165:115416
Histone lactylation-induced GLI3 activation drives macrophage M1 polarization and exosomal SERPINE1 release in abdominal aortic aneurysm progression.
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Cell death discovery 2025 Nov 10;11(1):523
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Choline Phosphate Surface-Activated 3D-Printed Porous Titanium Scaffold Combined with Stem Cell Exosomes for Enhancing Bone Defects Repair.
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ACS applied materials & interfaces 2025 May 14;17(19):27788-27805
ACS applied materials & interfaces 2025 May 14;17(19):27788-27805
Microneedle-mediated hypoxic extracellular vesicle-encapsulated selenium nanoparticles delivery to treat androgenetic alopecia.
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Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113597
Journal of controlled release : official journal of the Controlled Release Society 2025 May 10;381:113597
Decorin-mediated dermal papilla cell-derived exosomes regulate hair follicle growth and development through miR-129-2-3p/SMAD3/TGF-β axis.
Li J, Zhao B, Yu Y, Bao Z, Zheng F, Cai J, Chen Y, Wu X
International journal of biological macromolecules 2025 Mar;295:139292
International journal of biological macromolecules 2025 Mar;295:139292
Tremella polysaccharide microneedles loaded with magnetic dental pulp stem cell intracellular vesicles used for androgenic alopecia.
Liu Y, Zhou H, Pang P, Liu Y, Situ J, Wang J, He Y, Ye Q
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Stem cell research & therapy 2025 Mar 31;16(1):161
Bone marrow mesenchymal stem cell exosomes improve fracture union via remodeling metabolism in nonunion rat model.
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Journal of orthopaedic surgery and research 2025 Mar 25;20(1):308
Journal of orthopaedic surgery and research 2025 Mar 25;20(1):308
Psychological stress-induced ALKBH5 deficiency promotes tumour innervation and pancreatic cancer via extracellular vesicle transfer of RNA.
Chen Z, Zhou Y, Xue C, Zeng L, Deng S, Xu Z, Li M, Zhao H, He X, Liu S, Liu J, Liu S, Zhao S, Zhang S, Peng X, Wu X, Bai R, Zhuang L, Wu S, Zhang J, Lin D, Huang X, Zheng J
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ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554
ACS applied materials & interfaces 2025 Jun 11;17(23):33540-33554
Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.
Dong C, Zhou Y, Shen X, Hu S, Duan K, Chen T, Li W, Sun X, Li P, Wang P, Han Y, Li D, Zhi Q, Zhou J
Cell death & disease 2025 Jun 11;16(1):444
Cell death & disease 2025 Jun 11;16(1):444
Transdermal psoriasis treatment inspired by tumor microenvironment-mediated immunomodulation and advanced by exosomal engineering.
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Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113664
Journal of controlled release : official journal of the Controlled Release Society 2025 Jun 10;382:113664
Exploring Exosome Contributions to Gouty Arthritis: A Proteomics and Experimental Study.
Lu C, Yang X, Wang X, Wang Y, Zhang B, Lin Z
International journal of molecular sciences 2025 Jun 1;26(11)
International journal of molecular sciences 2025 Jun 1;26(11)
(124)I-labelled BMSC-Derived Extracellular Vesicles Deliver CRISPR/Cas9 Ribonucleoproteins With a GFP-Reporter System to Inhibit Osteosarcoma Proliferation and Metastasis.
Pan Y, Yang X, Zeng Z, Liu F, Luo J, Shen M, Zhou W, Li J, Jiang G, Sun L, Huang H, Pan R
Journal of extracellular vesicles 2025 Jul;14(7):e70130
Journal of extracellular vesicles 2025 Jul;14(7):e70130
Low-intensity pulsed ultrasound as a strategy to boost exosome secretion by adipose-derived stem cells and uptake for myocardial infarction therapy.
Jiang R, Wang H, Zhong F, Hu Y, Liu J, Chen Y, Su W, Cao S, Deng Q, Zhou Q
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)
Biomedical materials (Bristol, England) 2025 Jul 9;20(4)
Glutamine binds HSC70 to transduce signals inhibiting IFN-β-mediated immunogenic cell death.
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Developmental cell 2025 Jul 21;60(14):1958-1973.e9
Developmental cell 2025 Jul 21;60(14):1958-1973.e9
Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology.
Mohan HM, Fernandez MG, Huang C, Lin R, Ryou JH, Seyfried D, Grotewold N, Barget AJ, Whiteley AM, Basrur V, Mosalaganti S, Paulson HL, Sharkey LM
Science advances 2025 Jul 18;11(29):eadu6354
Science advances 2025 Jul 18;11(29):eadu6354
Exosomal circ_0006896 promotes AML progression via interaction with HDAC1 and restriction of antitumor immunity.
Can C, Yang X, Jia H, Wu H, Guo X, Wei Y, Jia Z, Liu W, Zhang A, He N, Zhang H, Ma D
Molecular cancer 2025 Jan 6;24(1):4
Molecular cancer 2025 Jan 6;24(1):4
Identifying plasma exosome antigens as a potential diagnostic biomarker for tuberculosis disease.
Jiang Y, Yan L, Zhou B, Hong J, Tan H, Li X, Wang Y
BMC infectious diseases 2025 Jan 14;25(1):65
BMC infectious diseases 2025 Jan 14;25(1):65
Hypoxia-Challenged Pancreatic Adenocarcinoma Cell-Derived Exosomal circR3HCC1L Drives Tumor Growth Via Upregulating PKM2 Through Sequestering miR-873-5p.
Wang L, Zhou S, Ruan Y, Wu X, Zhang X, Li Y, Ying D, Lu Y, Tian Y, Cheng G, Zhang J, Lv K, Zhou X
Molecular biotechnology 2025 Feb;67(2):762-777
Molecular biotechnology 2025 Feb;67(2):762-777
The expression and clinical significance of serum exosomal-long non-coding RNA DLEU1 in patients with cervical cancer.
Chen Y, Cui F, Wu X, Zhao W, Xia Q
Annals of medicine 2025 Dec;57(1):2442537
Annals of medicine 2025 Dec;57(1):2442537
Engineered BMSC-derived exosomes deliver miR-17-5p inhibitor to restore sensory conduction via the IL-11/GP130/STAT3/GAP-43 axis in dorsal column lesion.
Wang Z, Zhang M, Wang F, Wang X, Song X, Wang X, Zhang L, Ren L, Jing X, Yang L, Wang T
International journal of biological macromolecules 2025 Dec;334(Pt 1):148958
International journal of biological macromolecules 2025 Dec;334(Pt 1):148958
Microglia-specific interleukin-4 delivery by engineered extracellular vesicles restores inner blood-retinal barrier in diabetic retinopathy via GAS6-MERTK pathway.
Fan Y, Ge P, Wang X, Xu J, Wang J, Li H, Gu Q, Xie H, Lin Y, Lu Y, Wang C, Xie P, Hu Z
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Journal of nanobiotechnology 2025 Dec 29;24(1):101
Exosome-mediated modulation of macrophage polarization and inflammation in early Klebsiella pneumoniae lung infections.
Liu Z, Ren P, Xue Y, Liu S, Li S, Li Y, Zhang Y
Clinical science (London, England : 1979) 2025 Dec 23;139(24):1691-1707
Clinical science (London, England : 1979) 2025 Dec 23;139(24):1691-1707
Exosomal miR-223-3p from mesenchymal stem cells targets FBXW7 to inhibit intervertebral disc degeneration: mechanism insights.
Chen R, Cao K, Gong Y, Zhu Y, Pan W, Zhou Q
Journal of orthopaedic surgery and research 2025 Dec 10;21(1)
Journal of orthopaedic surgery and research 2025 Dec 10;21(1)
Vascular Smooth Muscle-Secreted Exosomal X26nt Impedes Atherosclerosis Progression via the c-FOS/XBP1/SOD1 Axis.
Zhang Z, Liu D, Zheng Y, Liu Y, Cheng X, Chang Y, Liang X, Hu X, Gao W
Immunity, inflammation and disease 2025 Aug;13(8):e70251
Immunity, inflammation and disease 2025 Aug;13(8):e70251
Engineered brain-targeting exosome for reprogramming immunosuppressive microenvironment of glioblastoma.
Yang J, Li Y, Jiang S, Tian Y, Zhang M, Guo S, Wu P, Li J, Xu L, Li W, Wang Y, Gao H, Huang Y, Weng Y, Ruan S
Exploration (Beijing, China) 2025 Apr;5(2):20240039
Exploration (Beijing, China) 2025 Apr;5(2):20240039
Blockade of Exosome Release Sensitizes Breast Cancer to Doxorubicin via Inhibiting Angiogenesis.
He J, He F, Yang Q, Li Q
Cancer medicine 2025 Apr;14(8):e70785
Cancer medicine 2025 Apr;14(8):e70785
LAMTOR1 decreased exosomal PD-L1 to enhance immunotherapy efficacy in non-small cell lung cancer.
Wu B, Huang X, Shi X, Jiang M, Liu H, Zhao L
Molecular cancer 2024 Sep 2;23(1):184
Molecular cancer 2024 Sep 2;23(1):184
Functional exosomes modified with chitosan effectively alleviate anthracycline-induced cardiotoxicity.
Wen Z, Qin S, Huang H, Xia X, Zhang W, Wu W
International journal of biological macromolecules 2024 Oct;277(Pt 3):134495
International journal of biological macromolecules 2024 Oct;277(Pt 3):134495
Plasma-derived exosome miR-10a-5p promotes premature ovarian failure by target BDNF via the TrkB/Akt/mTOR signaling pathway.
Bao Z, Li J, Cai J, Yao S, Yang N, Yang J, Zhao B, Chen Y, Wu X
International journal of biological macromolecules 2024 Oct;277(Pt 1):134195
International journal of biological macromolecules 2024 Oct;277(Pt 1):134195
Research on the role of exosomes secreted by immortalized adipose-derived mesenchymal stem cells differentiated into pericytes in the repair of high glucose-induced retinal vascular endothelial cell damage.
Wu S, Zhang Y, Hou Y, Zhu J, Yang H, Cui Y
Experimental eye research 2024 Oct;247:110046
Experimental eye research 2024 Oct;247:110046
Disease-derived circulating extracellular vesicle preconditioning: A promising strategy for precision mesenchymal stem cell therapy.
Lv K, Wu T, Liu S, Lou P, Zhou P, Wang Y, Zhou X, Zhang S, Du D, Lu Y, Wan M, Liu J
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4526-4543
Acta pharmaceutica Sinica. B 2024 Oct;14(10):4526-4543
Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and alter their functional properties.
Mohan HM, Fernandez MG, Huang C, Lin R, Ryou JH, Seyfried D, Grotewold N, Whiteley AM, Barmada SJ, Basrur V, Mosalaganti S, Paulson HL, Sharkey LM
bioRxiv : the preprint server for biology 2024 Oct 25;
bioRxiv : the preprint server for biology 2024 Oct 25;
Circulating extracellular vesicles from severe COVID-19 patients induce lung inflammation.
Qian H, Zang R, Zhang R, Zheng G, Qiu G, Meng J, Wang J, Xia J, Huang R, Le Z, Shu Q, Xu J
mSphere 2024 Nov 21;9(11):e0076424
mSphere 2024 Nov 21;9(11):e0076424
Dexamethasone-Integrated Mesenchymal Stem Cells for Systemic Lupus Erythematosus Treatment via Multiple Immunomodulatory Mechanisms.
Ma W, Che J, Chen W, Wang D, Zhang H, Zhao Y
ACS nano 2024 May 21;18(20):13249-13265
ACS nano 2024 May 21;18(20):13249-13265
Exosomes From IgE-Stimulated Mast Cells Aggravate Asthma-Mediated Atherosclerosis Through circRNA CDR1as-Mediated Endothelial Cell Dysfunction in Mice.
Yang H, Chen J, Liu S, Xue Y, Li Z, Wang T, Jiao L, An Q, Liu B, Wang J, Zhao H
Arteriosclerosis, thrombosis, and vascular biology 2024 Mar;44(3):e99-e115
Arteriosclerosis, thrombosis, and vascular biology 2024 Mar;44(3):e99-e115
ALIX and TSG101 are essential for cellular entry and replication of two porcine alphacoronaviruses.
Chen X, Liang Y, Weng Z, Hu C, Peng Y, Sun Y, Gao Q, Huang Z, Tang S, Gong L, Zhang G
PLoS pathogens 2024 Mar;20(3):e1012103
PLoS pathogens 2024 Mar;20(3):e1012103
Extracellular vesicles from human urine-derived stem cells delay aging through the transfer of PLAU and TIMP1.
Rao S, He Z, Wang Z, Yin H, Hu X, Tan Y, Wan T, Zhu H, Luo Y, Wang X, Li H, Wang Z, Hu X, Hong C, Wang Y, Luo M, Du W, Qian Y, Tang S, Xie H, Chen C
Acta pharmaceutica Sinica. B 2024 Mar;14(3):1166-1186
Acta pharmaceutica Sinica. B 2024 Mar;14(3):1166-1186
Blood-based CNS regionally and neuronally enriched extracellular vesicles carrying pTau217 for Alzheimer's disease diagnosis and differential diagnosis.
Guo Z, Tian C, Shi Y, Song XR, Yin W, Tao QQ, Liu J, Peng GP, Wu ZY, Wang YJ, Zhang ZX, Zhang J
Acta neuropathologica communications 2024 Mar 5;12(1):38
Acta neuropathologica communications 2024 Mar 5;12(1):38
Calmodulin-like 5 promotes PEDV replication by regulating late-endosome synthesis and innate immune response.
Tian WJ, Zhang XZ, Wang J, Liu JF, Li FH, Wang XJ
Virologica Sinica 2024 Jun;39(3):501-512
Virologica Sinica 2024 Jun;39(3):501-512
Bone marrow-fibroblast progenitor cell-derived small extracellular vesicles promote cardiac fibrosis via miR-21-5p and integrin subunit αV signalling.
Ranjan P, Dutta RK, Colin K, Li J, Zhang Q, Lal H, Qin G, Verma SK
Journal of extracellular biology 2024 Jun;3(6):e152
Journal of extracellular biology 2024 Jun;3(6):e152
AS1411 binds to nucleolin via its parallel structure and disrupts the exos-miRNA-27a-mediated reciprocal activation loop between glioma and astrocytes.
Sun X, Zhang W, Gou C, Wang X, Wang X, Shao X, Chen X, Chen Z
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167211
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167211
Baohuoside I chemosensitises breast cancer to paclitaxel by suppressing extracellular vesicle/CXCL1 signal released from apoptotic cells.
Wang S, Li J, Xu S, Wang N, Pan B, Yang B, Zheng Y, Zhang J, Peng F, Peng C, Wang Z
Journal of extracellular vesicles 2024 Jul;13(7):e12493
Journal of extracellular vesicles 2024 Jul;13(7):e12493
Local Delivery of Dual Stem Cell-Derived Exosomes Using an Electrospun Nanofibrous Platform for the Treatment of Traumatic Brain Injury.
Li J, Li X, Li X, Liang Z, Wang Z, Shahzad KA, Xu M, Tan F
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
ACS applied materials & interfaces 2024 Jul 24;16(29):37497-37512
Exosomes from adipose-derived stem cells overexpressing microRNA-671-3p promote fat graft angiogenesis and adipogenic differentiation.
Hao X, Guo Y, Yu X, He L, He Y, Shu M
Tissue & cell 2024 Dec;91:102575
Tissue & cell 2024 Dec;91:102575
Subcellular localization of viral proteins after porcine epidemic diarrhea virus infection and their roles in the viral life cycle.
Chen XN, Cai ST, Liang YF, Weng ZJ, Song TQ, Li X, Sun YS, Peng YZ, Huang Z, Gao Q, Tang SQ, Zhang GH, Gong L
International journal of biological macromolecules 2024 Aug;274(Pt 2):133401
International journal of biological macromolecules 2024 Aug;274(Pt 2):133401
3D-hUMSCs Exosomes Ameliorate Vitiligo by Simultaneously Potentiating Treg Cells-Mediated Immunosuppression and Suppressing Oxidative Stress-Induced Melanocyte Damage.
Wang Q, Guo W, Niu L, Zhou Y, Wang Z, Chen J, Chen J, Ma J, Zhang J, Jiang Z, Wang B, Zhang Z, Li C, Jian Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2404064
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Aug;11(31):e2404064
Targeted treatment of rat AKI induced by rhabdomyolysis using BMSC derived magnetic exosomes and its mechanism.
Chen Y, Hou S
Nanoscale advances 2024 Aug 6;6(16):4180-4195
Nanoscale advances 2024 Aug 6;6(16):4180-4195
Locally delivered hydrogels with controlled release of nanoscale exosomes promote cardiac repair after myocardial infarction.
Tan X, Zhang J, Heng Y, Chen L, Wang Y, Wu S, Liu X, Xu B, Yu Z, Gu R
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:303-317
Journal of controlled release : official journal of the Controlled Release Society 2024 Apr;368:303-317
Hepatocyte-derived exosomes deliver the lncRNA CYTOR to hepatic stellate cells and promote liver fibrosis.
Xu W, Mo W, Han D, Dai W, Xu X, Li J, Xu X
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234
Journal of cellular and molecular medicine 2024 Apr;28(8):e18234
Chemotherapy-elicited extracellular vesicle CXCL1 from dying cells promotes triple-negative breast cancer metastasis by activating TAM/PD-L1 signaling.
Wang S, Li J, Hong S, Wang N, Xu S, Yang B, Zheng Y, Zhang J, Pan B, Hu Y, Wang Z
Journal of experimental & clinical cancer research : CR 2024 Apr 23;43(1):121
Journal of experimental & clinical cancer research : CR 2024 Apr 23;43(1):121
Dysregulation of MicroRNAs Derived from Plasma Extracellular Vesicles in Schizoaffective Disorder.
Chen R, Shi J, Yang H, Zhang M, Chen Q, He Q
Molecular neurobiology 2023 Nov;60(11):6373-6382
Molecular neurobiology 2023 Nov;60(11):6373-6382
Exosomes derived from schwann cells alleviate mitochondrial dysfunction and necroptosis after spinal cord injury via AMPK signaling pathway-mediated mitophagy.
Xu B, Zhou Z, Fang J, Wang J, Tao K, Liu J, Liu S
Free radical biology & medicine 2023 Nov 1;208:319-333
Free radical biology & medicine 2023 Nov 1;208:319-333
Engineered Microparticles for Treatment of Murine Brain Metastasis by Reprograming Tumor Microenvironment and Inhibiting MAPK Pathway.
Lu L, Zi H, Zhou J, Huang J, Deng Z, Tang Z, Li L, Shi X, Lo PC, Lovell JF, Deng D, Wan C, Jin H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Mar;10(8):e2206212
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Mar;10(8):e2206212
Exosomal ZEB1 Derived from Neural Stem Cells Reduces Inflammation Injury in OGD/R-Treated Microglia via the GPR30-TLR4-NF-κB Axis.
Peng J, Yu Z, Xiao R, Hu X, Xia Y
Neurochemical research 2023 Jun;48(6):1811-1821
Neurochemical research 2023 Jun;48(6):1811-1821
Exosomal ERBB2IP contributes to tumor growth via elevating PSAT1 expression in non-small cell lung carcinoma.
Peng X, Zhao L, Yao L, Dong J, Wu W, Luo T
Thoracic cancer 2023 Jul;14(19):1812-1823
Thoracic cancer 2023 Jul;14(19):1812-1823
Dermal PapillaCell-Derived Exosomes Regulate Hair Follicle Stem Cell Proliferation via LEF1.
Li J, Zhao B, Yao S, Dai Y, Zhang X, Yang N, Bao Z, Cai J, Chen Y, Wu X
International journal of molecular sciences 2023 Feb 16;24(4)
International journal of molecular sciences 2023 Feb 16;24(4)
A method for extraction of exosomes from breast tumour cells and characterisation by transmission electron microscopy.
Liu Z, Xue H, Chen Q, Yang G
Journal of microscopy 2023 Dec;292(3):117-122
Journal of microscopy 2023 Dec;292(3):117-122
Hedgehog-Gli1-derived exosomal circ-0011536 mediates peripheral neural remodeling in pancreatic cancer by modulating the miR-451a/VGF axis.
Dai W, Wu X, Li J, Tang W, Wang Y, Xu W, Han D, Xu X, Xu X
Journal of experimental & clinical cancer research : CR 2023 Dec 2;42(1):329
Journal of experimental & clinical cancer research : CR 2023 Dec 2;42(1):329
Circulating Exosomal miR-181b-5p Promoted Cell Senescence and Inhibited Angiogenesis to Impair Diabetic Foot Ulcer via the Nuclear Factor Erythroid 2-Related Factor 2/Heme Oxygenase-1 Pathway.
Wang S, Shi M, Zhou J, Wang W, Zhang Y, Li Y
Frontiers in cardiovascular medicine 2022;9:844047
Frontiers in cardiovascular medicine 2022;9:844047
Exosomes Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation through the Wnt3a/β-Catenin Signaling Pathway.
Li J, Zhao B, Dai Y, Zhang X, Chen Y, Wu X
Oxidative medicine and cellular longevity 2022;2022:9042345
Oxidative medicine and cellular longevity 2022;2022:9042345
Adipose-Derived Circulating Exosomes Promote Protection of the Pulmonary Endothelial Barrier by Inhibiting EndMT and Oxidative Stress through Down-Regulation of the TGF-β Pathway: A Potential Explanation for the Obesity Paradox in ARDS.
Qi D, Deng W, Chen X, Fan S, Peng J, Tang X, Wang D, Yu Q
Oxidative medicine and cellular longevity 2022;2022:5475832
Oxidative medicine and cellular longevity 2022;2022:5475832
Engineered Exosomes-Mediated Transfer of hsa-miR-320a Overcomes Chemoresistance in Cervical Cancer Cells via Targeting MCL1.
Zhou J, Wang Y, Zhang L, Chen Q, Zhu X, Jiang P, Jiang N, Zhao W, Li B
Frontiers in pharmacology 2022;13:883445
Frontiers in pharmacology 2022;13:883445
Loss of exosomal micro-RNA-200b-3p from hypoxia cancer-associated fibroblasts reduces sensitivity to 5-flourouracil in colorectal cancer through targeting high-mobility group box 3.
Yuan H, Chen B, Chai R, Gong W, Wan Z, Zheng B, Hu X, Guo Y, Gao S, Dai Q, Yu P, Tu S
Frontiers in oncology 2022;12:920131
Frontiers in oncology 2022;12:920131
Safety and biodistribution of exosomes derived from human induced pluripotent stem cells.
Gu Z, Yin Z, Song P, Wu Y, He Y, Zhu M, Wu Z, Zhao S, Huang H, Wang H, Tong C, Qi Z
Frontiers in bioengineering and biotechnology 2022;10:949724
Frontiers in bioengineering and biotechnology 2022;10:949724
Injectable cartilage matrix hydrogel loaded with cartilage endplate stem cells engineered to release exosomes for non-invasive treatment of intervertebral disc degeneration.
Luo L, Gong J, Wang Z, Liu Y, Cao J, Qin J, Zuo R, Zhang H, Wang S, Zhao P, Yang D, Zhang M, Wang Y, Zhang J, Zhou Y, Li C, Ni B, Tian Z, Liu M
Bioactive materials 2022 Sep;15:29-43
Bioactive materials 2022 Sep;15:29-43
Downregulation of exosomal miR-7-5p promotes breast cancer migration and invasion by targeting RYK and participating in the atypical WNT signalling pathway.
Liang Z, Liu L, Gao R, Che C, Yang G
Cellular & molecular biology letters 2022 Oct 9;27(1):88
Cellular & molecular biology letters 2022 Oct 9;27(1):88
Exosomal miRNA-181a-5p from the cells of the hair follicle dermal papilla promotes the hair follicle growth and development via the Wnt/β-catenin signaling pathway.
Zhao B, Li J, Zhang X, Dai Y, Yang N, Bao Z, Chen Y, Wu X
International journal of biological macromolecules 2022 May 15;207:110-120
International journal of biological macromolecules 2022 May 15;207:110-120
Construction and analysis of expression profile of exosomal lncRNAs in pleural effusion in lung adenocarcinoma.
Huang X, Zhou H, Yang X, Shi W, Hu L, Wang J, Zhang F, Shao F, Zhang M, Jiang F, Wang Y
Journal of clinical laboratory analysis 2022 Dec;36(12):e24777
Journal of clinical laboratory analysis 2022 Dec;36(12):e24777
Proteomics Analysis of Exosomes From Patients With Active Tuberculosis Reveals Infection Profiles and Potential Biomarkers.
Zhang M, Xie Y, Li S, Ye X, Jiang Y, Tang L, Wang J
Frontiers in microbiology 2021;12:800807
Frontiers in microbiology 2021;12:800807
Extracellular vesicles derived from hypoxia-preconditioned olfactory mucosa mesenchymal stem cells enhance angiogenesis via miR-612.
Ge L, Xun C, Li W, Jin S, Liu Z, Zhuo Y, Duan D, Hu Z, Chen P, Lu M
Journal of nanobiotechnology 2021 Nov 21;19(1):380
Journal of nanobiotechnology 2021 Nov 21;19(1):380
Endothelial cell-derived exosomal circHIPK3 promotes the proliferation of vascular smooth muscle cells induced by high glucose via the miR-106a-5p/Foxo1/Vcam1 pathway.
Wang S, Shi M, Li J, Zhang Y, Wang W, Xu P, Li Y
Aging 2021 Dec 10;13(23):25241-25255
Aging 2021 Dec 10;13(23):25241-25255
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