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- Antigen structure
- References [23]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 24893-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- MRP2 antibody
- Antibody type
- Polyclonal
- Description
- MRP2 antibody (Cat. #24893-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Ursolic acid attenuates cholestasis through NRF2-mediated regulation of UGT2B7 and BSEP/MRP2.
The choleretic role of tauroursodeoxycholic acid exacerbates alpha-naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway.
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.
Knockdown of USP9X reverses cisplatin resistance by decreasing β-catenin expression in nasopharyngeal carcinoma cells.
The zonula occludens protein family regulates the hepatic barrier system in the murine liver.
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Tanshinone IIA attenuates acetaminophen-induced hepatotoxicity through HOTAIR-Nrf2-MRP2/4 signaling pathway.
Effect of sodium butyrate on ABC transporters in lung cancer A549 and colorectal cancer HCT116 cells.
Variability in the Clearance of Lead Oxide Nanoparticles Is Associated with Alteration of Specific Membrane Transporters.
Overexpression of RSK4 reverses doxorubicin resistance in human breast cancer cells via PI3K/AKT signalling pathway.
Prognostic Implication of a Metabolism-Associated Gene Signature in Lung Adenocarcinoma.
Generation of hepatic spheroids using human hepatocyte-derived liver progenitor-like cells for hepatotoxicity screening.
Circadian Clock Gene Bmal1 Regulates Bilirubin Detoxification: A Potential Mechanism of Feedback Control of Hyperbilirubinemia.
Comparison of Pregnane X Receptor Antagonists for Enhancing the Antitumor Effect of Cisplatin.
Formononetin ameliorates cholestasis by regulating hepatic SIRT1 and PPARα.
Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers.
Effects of histone deacetylase inhibitors on ATP-binding cassette transporters in lung cancer A549 and colorectal cancer HCT116 cells.
Association between the perturbation of bile acid homeostasis and valproic acid-induced hepatotoxicity.
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner.
Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model.
Revival, characterization, and hepatitis B virus infection of cryopreserved human fetal hepatocytes.
Wang X, Xiong W, Wang X, Qin L, Zhong M, Liu Y, Xiong Y, Yi X, Wang X, Zhang H
Naunyn-Schmiedeberg's archives of pharmacology 2024 Apr;397(4):2257-2267
Naunyn-Schmiedeberg's archives of pharmacology 2024 Apr;397(4):2257-2267
The choleretic role of tauroursodeoxycholic acid exacerbates alpha-naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway.
Zhao J, Song G, Weng F, Li Y, Zou B, Jin J, Yan D, Sun X, Liu C, Qiu FR
Journal of applied toxicology : JAT 2023 Jul;43(7):1095-1103
Journal of applied toxicology : JAT 2023 Jul;43(7):1095-1103
HIF1α/VEGF Feedback Loop Contributes to 5-Fluorouracil Resistance.
Shi B, Xu FF, Xiang CP, Li CY, Fan P, Wang H
Frontiers in pharmacology 2022;13:851401
Frontiers in pharmacology 2022;13:851401
Knockdown of USP9X reverses cisplatin resistance by decreasing β-catenin expression in nasopharyngeal carcinoma cells.
Lu WX, Gan GS, Yang B
Neoplasma 2021 Jul;68(4):810-822
Neoplasma 2021 Jul;68(4):810-822
The zonula occludens protein family regulates the hepatic barrier system in the murine liver.
Itoh M, Terada M, Sugimoto H
Biochimica et biophysica acta. Molecular basis of disease 2021 Jan 1;1867(1):165994
Biochimica et biophysica acta. Molecular basis of disease 2021 Jan 1;1867(1):165994
The AKT/GSK3-Mediated Slug Expression Contributes to Oxaliplatin Resistance in Colorectal Cancer via Upregulation of ERCC1.
Wei W, Ma XD, Jiang GM, Shi B, Zhong W, Sun CL, Zhao L, Hou YJ, Wang H
Oncology research 2020 Sep 1;28(4):423-438
Oncology research 2020 Sep 1;28(4):423-438
Tanshinone IIA attenuates acetaminophen-induced hepatotoxicity through HOTAIR-Nrf2-MRP2/4 signaling pathway.
Zhang X, Wang T, Yang Y, Li R, Chen Y, Li R, Jiang X, Wang L
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110547
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Oct;130:110547
Effect of sodium butyrate on ABC transporters in lung cancer A549 and colorectal cancer HCT116 cells.
Shi B, Xu FF, Xiang CP, Jia R, Yan CH, Ma SQ, Wang N, Wang AJ, Fan P
Oncology letters 2020 Nov;20(5):148
Oncology letters 2020 Nov;20(5):148
Variability in the Clearance of Lead Oxide Nanoparticles Is Associated with Alteration of Specific Membrane Transporters.
Dumková J, Smutná T, Vrlíková L, Kotasová H, Dočekal B, Čapka L, Tvrdoňová M, Jakešová V, Pelková V, Křůmal K, Coufalík P, Mikuška P, Večeřa Z, Vaculovič T, Husáková Z, Kanický V, Hampl A, Buchtová M
ACS nano 2020 Mar 24;14(3):3096-3120
ACS nano 2020 Mar 24;14(3):3096-3120
Overexpression of RSK4 reverses doxorubicin resistance in human breast cancer cells via PI3K/AKT signalling pathway.
Mei Y, Liao X, Zhu L, Yang H
Journal of biochemistry 2020 Jun 1;167(6):603-611
Journal of biochemistry 2020 Jun 1;167(6):603-611
Prognostic Implication of a Metabolism-Associated Gene Signature in Lung Adenocarcinoma.
He L, Chen J, Xu F, Li J, Li J
Molecular therapy oncolytics 2020 Dec 16;19:265-277
Molecular therapy oncolytics 2020 Dec 16;19:265-277
Generation of hepatic spheroids using human hepatocyte-derived liver progenitor-like cells for hepatotoxicity screening.
Wang Z, Li W, Jing H, Ding M, Fu G, Yuan T, Huang W, Dai M, Tang D, Zeng M, Chen Y, Zhang H, Zhu X, Peng Y, Li Q, Yu WF, Yan HX, Zhai B
Theranostics 2019;9(22):6690-6705
Theranostics 2019;9(22):6690-6705
Circadian Clock Gene Bmal1 Regulates Bilirubin Detoxification: A Potential Mechanism of Feedback Control of Hyperbilirubinemia.
Wang S, Lin Y, Zhou Z, Gao L, Yang Z, Li F, Wu B
Theranostics 2019;9(18):5122-5133
Theranostics 2019;9(18):5122-5133
Comparison of Pregnane X Receptor Antagonists for Enhancing the Antitumor Effect of Cisplatin.
Yasuda M, Kishimoto S, Amano M, Fukushima S
Anticancer research 2019 Sep;39(9):4749-4755
Anticancer research 2019 Sep;39(9):4749-4755
Formononetin ameliorates cholestasis by regulating hepatic SIRT1 and PPARα.
Yang S, Wei L, Xia R, Liu L, Chen Y, Zhang W, Li Q, Feng K, Yu M, Zhang W, Qu J, Xu S, Mao J, Fan G, Ma C
Biochemical and biophysical research communications 2019 May 14;512(4):770-778
Biochemical and biophysical research communications 2019 May 14;512(4):770-778
Effect of Stereochemical Configuration on the Transport and Metabolism of Catechins from Green Tea across Caco-2 Monolayers.
Ai Z, Liu S, Qu F, Zhang H, Chen Y, Ni D
Molecules (Basel, Switzerland) 2019 Mar 26;24(6)
Molecules (Basel, Switzerland) 2019 Mar 26;24(6)
Effects of histone deacetylase inhibitors on ATP-binding cassette transporters in lung cancer A549 and colorectal cancer HCT116 cells.
Wang H, Chi CH, Zhang Y, Shi B, Jia R, Wang BJ
Oncology letters 2019 Jul;18(1):63-71
Oncology letters 2019 Jul;18(1):63-71
Association between the perturbation of bile acid homeostasis and valproic acid-induced hepatotoxicity.
Chen Y, Zhou J, Xu S, Liu M, Wang M, Ma Y, Zhao M, Wang Z, Guo Y, Zhao L
Biochemical pharmacology 2019 Dec;170:113669
Biochemical pharmacology 2019 Dec;170:113669
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Ning C, Gao X, Wang C, Kong Y, Liu Z, Sun H, Sun P, Huo X, Ma X, Meng Q, Liu K
Regulatory toxicology and pharmacology : RTP 2018 Oct;98:58-68
Regulatory toxicology and pharmacology : RTP 2018 Oct;98:58-68
Hepatic, Metabolic, and Toxicity Evaluation of Repeated Oral Administration of SnS2 Nanoflowers in Mice.
Bai D, Li Q, Xiong Y, Wang C, Shen P, Bai L, Yuan L, Wu P
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
Toxicological sciences : an official journal of the Society of Toxicology 2018 Aug 1;164(2):501-511
MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner.
Jin W, Liao X, Lv Y, Pang Z, Wang Y, Li Q, Liao Y, Ye Q, Chen G, Zhao K, Huang L
Cell death & disease 2017 Aug 10;8(8):e2980
Cell death & disease 2017 Aug 10;8(8):e2980
Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model.
Ni X, Gao Y, Wu Z, Ma L, Chen C, Wang L, Lin Y, Hui L, Pan G
Scientific reports 2016 Dec 9;6:38694
Scientific reports 2016 Dec 9;6:38694
Revival, characterization, and hepatitis B virus infection of cryopreserved human fetal hepatocytes.
Zhou M, Huang Y, Cheng Z, Zhao F, Li J, Zhi X, Tian X, Sun W, Hu K
Journal of virological methods 2014 Oct;207:29-37
Journal of virological methods 2014 Oct;207:29-37
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 24893-1-AP( ABCC2 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The MRP2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human MRP2. This antibody recognizes human, mouse antigen. The MRP2 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
