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- Antibody Data
- Antigen structure
- References [5]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN954896 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-SP140 Nuclear Body Protein (SP140) (AA 279-309), (Middle Region) antibody
- Antibody type
- Polyclonal
- Antigen
- KLH conjugated synthetic peptide between 279-309 amino acids from the Central region of Human SP140. Genename: SP140
- Description
- Protein A column, followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 279-309,Middle Region
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Genetic susceptibility variants for chronic lymphocytic leukemia.
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.
Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1.
Identification and characterization of a leukocyte-specific component of the nuclear body.
LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies.
Slager SL, Goldin LR, Strom SS, Lanasa MC, Spector LG, Rassenti L, Leis JF, Camp NJ, Kay NE, Vachon CM, Glenn M, Weinberg JB, Rabe KG, Cunningham JM, Achenbach SJ, Hanson CA, Marti GE, Call TG, Caporaso NE, Cerhan JR
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 Apr;19(4):1098-102
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 Apr;19(4):1098-102
A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia.
Di Bernardo MC, Crowther-Swanepoel D, Broderick P, Webb E, Sellick G, Wild R, Sullivan K, Vijayakrishnan J, Wang Y, Pittman AM, Sunter NJ, Hall AG, Dyer MJ, Matutes E, Dearden C, Mainou-Fowler T, Jackson GH, Summerfield G, Harris RJ, Pettitt AR, Hillmen P, Allsup DJ, Bailey JR, Pratt G, Pepper C, Fegan C, Allan JM, Catovsky D, Houlston RS
Nature genetics 2008 Oct;40(10):1204-10
Nature genetics 2008 Oct;40(10):1204-10
Implication of the lymphocyte-specific nuclear body protein Sp140 in an innate response to human immunodeficiency virus type 1.
Madani N, Millette R, Platt EJ, Marin M, Kozak SL, Bloch DB, Kabat D
Journal of virology 2002 Nov;76(21):11133-8
Journal of virology 2002 Nov;76(21):11133-8
Identification and characterization of a leukocyte-specific component of the nuclear body.
Bloch DB, de la Monte SM, Guigaouri P, Filippov A, Bloch KD
The Journal of biological chemistry 1996 Nov 15;271(46):29198-204
The Journal of biological chemistry 1996 Nov 15;271(46):29198-204
LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies.
Dent AL, Yewdell J, Puvion-Dutilleul F, Koken MH, de The H, Staudt LM
Blood 1996 Aug 15;88(4):1423-6
Blood 1996 Aug 15;88(4):1423-6
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of SP140 Antibody Cat.-No AP53989PU-N in HL-60 cell line lysates (35ug/lane).This demonstrates the SP140 antibody detected the SP140 protein (arrow).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin fixed, paraffin embedded human kidney tissue stained with SP140 Antibody Cat.-No AP53989PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SP140 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
