Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 22242-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- REST antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated REST antibody (Cat. #22242-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Comprehensive Analysis of REST/NRSF Gene in Glioma and Its ceRNA Network Identification.
YAP drives fate conversion and chemoresistance of small cell lung cancer.
NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice.
Novel REST Truncation Mutations Causing Hereditary Gingival Fibromatosis.
Remodeling of the m6A landscape in the heart reveals few conserved post-transcriptional events underlying cardiomyocyte hypertrophy.
ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling.
The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth.
Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury.
Inhibition of the Epigenetic Regulator REST Ameliorates Ischemic Brain Injury.
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Zhang Y, Wang Q, Wang Z, Zhang C, Xu X, Xu J, Ren H, Shao X, Zhen X, Zhang L, Yu Y
Frontiers in medicine 2021;8:739624
Frontiers in medicine 2021;8:739624
YAP drives fate conversion and chemoresistance of small cell lung cancer.
Wu Q, Guo J, Liu Y, Zheng Q, Li X, Wu C, Fang D, Chen X, Ma L, Xu P, Xu X, Liao C, Wu M, Shen L, Song H
Science advances 2021 Oct;7(40):eabg1850
Science advances 2021 Oct;7(40):eabg1850
NLRP3 Inflammasome Activation Enhances ADK Expression to Accelerate Epilepsy in Mice.
Zhang H, Yu S, Xia L, Peng X, Wang S, Yao B
Neurochemical research 2021 Nov 19;
Neurochemical research 2021 Nov 19;
Novel REST Truncation Mutations Causing Hereditary Gingival Fibromatosis.
Chen JT, Lin CH, Huang HW, Wang YP, Kao PC, Yang TP, Wang SK
Journal of dental research 2021 Jul;100(8):868-874
Journal of dental research 2021 Jul;100(8):868-874
Remodeling of the m6A landscape in the heart reveals few conserved post-transcriptional events underlying cardiomyocyte hypertrophy.
Hinger SA, Wei J, Dorn LE, Whitson BA, Janssen PML, He C, Accornero F
Journal of molecular and cellular cardiology 2021 Feb;151:46-55
Journal of molecular and cellular cardiology 2021 Feb;151:46-55
ALKBH5-mediated m6A demethylation of KCNK15-AS1 inhibits pancreatic cancer progression via regulating KCNK15 and PTEN/AKT signaling.
He Y, Yue H, Cheng Y, Ding Z, Xu Z, Lv C, Wang Z, Wang J, Yin C, Hao H, Chen C
Cell death & disease 2021 Dec 1;12(12):1121
Cell death & disease 2021 Dec 1;12(12):1121
The cross talk of two family members of β-TrCP in the regulation of cell autophagy and growth.
Cui D, Dai X, Shu J, Ma Y, Wei D, Xiong X, Zhao Y
Cell death and differentiation 2020 Mar;27(3):1119-1133
Cell death and differentiation 2020 Mar;27(3):1119-1133
Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury.
Bray JK, Elgamal OA, Jiang J, Wright LS, Sutaria DS, Badawi M, Borcyk MG, Liu X, Fredenburg KM, Campbell-Thompson ML, Schmittgen TD
Cell death & disease 2020 Feb 20;11(2):138
Cell death & disease 2020 Feb 20;11(2):138
Inhibition of the Epigenetic Regulator REST Ameliorates Ischemic Brain Injury.
Morris-Blanco KC, Kim T, Bertogliat MJ, Mehta SL, Chokkalla AK, Vemuganti R
Molecular neurobiology 2019 Apr;56(4):2542-2550
Molecular neurobiology 2019 Apr;56(4):2542-2550
Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.
Song Z, Shah SZA, Yang W, Dong H, Yang L, Zhou X, Zhao D
Frontiers in molecular neuroscience 2017;10:128
Frontiers in molecular neuroscience 2017;10:128
Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.
Song Z, Yang W, Zhou X, Yang L, Zhao D
Neuropharmacology 2017 Sep 1;123:332-348
Neuropharmacology 2017 Sep 1;123:332-348
REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.
Song Z, Zhu T, Zhou X, Barrow P, Yang W, Cui Y, Yang L, Zhao D
Oncotarget 2016 Mar 15;7(11):12035-52
Oncotarget 2016 Mar 15;7(11):12035-52
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 22242-1-AP( REST Antibody) at dilution of 1:1500
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The REST antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human REST. This antibody recognizes human antigen. The REST antibody has been validated for the following applications: ELISA, WB analysis.