orb131750

antibody from Biorbyt

Targeting: REST DFNA27, NRSF, XBR

Western blot

Antibody data

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Validation data

Product number: orb131750 - Provider product page
Provider: Biorbyt
Product name: REST antibody
Antibody type: Polyclonal
Description: Rabbit polyclonal to REST. RE1-silencing transcription factor (REST) is a transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. REST restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Additionally, REST mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Vial size: 100 ul
Concentration: 100 μg/ml BSA
Storage: -20°C

REST protein structure - orb131750 shown in red.