Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
Reference
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- Product number
- 11135-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11135-1-AP, RRID:AB_2229682
- Product name
- CNOT3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CNOT3 antibody (Cat. #11135-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Highly efficient identification of nucleocytoplasmic O-glycosylation by the TurboID-based proximity labeling method in living cells.
Regulation by the RNA-binding protein Unkempt at its effector interface.
A paradigm for regulation at the effector interface with RNA-binding proteins.
Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance.
Targeting the up-regulated CNOT3 reverses therapeutic resistance and metastatic progression of EGFR-mutant non-small cell lung cancer.
Disruption of the Mammalian Ccr4-Not Complex Contributes to Transcription-Mediated Genome Instability.
CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21.
CNOT3 contributes to cisplatin resistance in lung cancer through inhibiting RIPK3 expression.
Alternative splicing of CNOT7 diversifies CCR4-NOT functions.
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.
Long Y, Li Z, Wang L, Ao X, Zhang Z, Chen Q, Zhu D, Liu X, Liu R, Chen B, Zhu H, Su Y
Biotechnology journal 2024 Jan;19(1):e2300090
Biotechnology journal 2024 Jan;19(1):e2300090
Regulation by the RNA-binding protein Unkempt at its effector interface.
Shah K, He S, Turner DJ, Corbo J, Rebbani K, Dominguez D, Bateman JM, Cheloufi S, Igreja C, Valkov E, Murn J
Nature communications 2024 Apr 11;15(1):3159
Nature communications 2024 Apr 11;15(1):3159
A paradigm for regulation at the effector interface with RNA-binding proteins.
Shah K, He S, Turner DJ, Corbo J, Rebbani K, Bateman JM, Cheloufi S, Igreja C, Valkov E, Murn J
bioRxiv : the preprint server for biology 2023 Oct 24;
bioRxiv : the preprint server for biology 2023 Oct 24;
Cnot3 is required for male germ cell development and spermatogonial stem cell maintenance.
Chen Q, Malki S, Xu X, Bennett B, Lackford BL, Kirsanov O, Geyer CB, Hu G
bioRxiv : the preprint server for biology 2023 Oct 14;
bioRxiv : the preprint server for biology 2023 Oct 14;
Targeting the up-regulated CNOT3 reverses therapeutic resistance and metastatic progression of EGFR-mutant non-small cell lung cancer.
Jing L, Zhai ME, Qian MR, Li YM, Han MW, Wang K, Huang W, Nan G, Jiang JL
Cell death discovery 2023 Nov 2;9(1):406
Cell death discovery 2023 Nov 2;9(1):406
Disruption of the Mammalian Ccr4-Not Complex Contributes to Transcription-Mediated Genome Instability.
Hagkarim NC, Hajkarim MC, Suzuki T, Fujiwara T, Winkler GS, Stewart GS, Grand RJ
Cells 2023 Jul 17;12(14)
Cells 2023 Jul 17;12(14)
CCR4-NOT differentially controls host versus virus poly(a)-tail length and regulates HCMV infection.
Burgess HM, Grande R, Riccio S, Dinesh I, Winkler GS, Depledge DP, Mohr I
EMBO reports 2023 Dec 6;24(12):e56327
EMBO reports 2023 Dec 6;24(12):e56327
ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1.
Zhang T, Sun L, Hao Y, Suo C, Shen S, Wei H, Ma W, Zhang P, Wang T, Gu X, Li ST, Chen Z, Yan R, Zhang Y, Cai Y, Zhou R, Jia W, Huang F, Gao P, Zhang H
Nature cancer 2022 Jan;3(1):75-89
Nature cancer 2022 Jan;3(1):75-89
An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21.
McRae EKS, Dupas SJ, Booy EP, Piragasam RS, Fahlman RP, McKenna SA
RNA (New York, N.Y.) 2020 Jan;26(1):44-57
RNA (New York, N.Y.) 2020 Jan;26(1):44-57
CNOT3 contributes to cisplatin resistance in lung cancer through inhibiting RIPK3 expression.
Jing L, Zhai ME, Cui J, Fan XY, Cheng YY, Jiang JL, Chen ZN
Apoptosis : an international journal on programmed cell death 2019 Aug;24(7-8):673-685
Apoptosis : an international journal on programmed cell death 2019 Aug;24(7-8):673-685
Alternative splicing of CNOT7 diversifies CCR4-NOT functions.
Chapat C, Chettab K, Simonet P, Wang P, De La Grange P, Le Romancer M, Corbo L
Nucleic acids research 2017 Aug 21;45(14):8508-8523
Nucleic acids research 2017 Aug 21;45(14):8508-8523
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.
Neely GG, Kuba K, Cammarato A, Isobe K, Amann S, Zhang L, Murata M, Elmén L, Gupta V, Arora S, Sarangi R, Dan D, Fujisawa S, Usami T, Xia CP, Keene AC, Alayari NN, Yamakawa H, Elling U, Berger C, Novatchkova M, Koglgruber R, Fukuda K, Nishina H, Isobe M, Pospisilik JA, Imai Y, Pfeufer A, Hicks AA, Pramstaller PP, Subramaniam S, Kimura A, Ocorr K, Bodmer R, Penninger JM
Cell 2010 Apr 2;141(1):142-53
Cell 2010 Apr 2;141(1):142-53
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Raji cells were subjected to SDS PAGE followed by western blot with 11135-1-AP(CNOT3 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using CNOT3 antibody 11135-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line