FNab01808

antibody from FineTest Biotech
Targeting: CNOT3 KIAA0691, LENG2, NOT3, NOT3H
Provider product page for FNab01808
Western blot
ELISA
Immunocytochemistry
Immunoprecipitation

Antibody data

Product number
FNab01808 - Provider product page
Provider
FineTest Biotech
Product name
CNOT3 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem(ES) cell identity.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
CCR4-NOT transcription complex, sub
unit 3
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
CNOT3 protein structure - FNab01808 shown in red.