Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11546-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11546-1-AP, RRID:AB_2153157
- Product name
- NMT1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NMT1 antibody (Cat. #11546-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Multiomics analysis identifies oxidative phosphorylation as a cancer vulnerability arising from myristoylation inhibition.
Series of Desloratadine Platinum(IV) Hybrids Displaying Potent Antimetastatic Competence by Inhibiting Epithelial-Mesenchymal Transition and Arousing Immune Response.
NMT1 sustains ICAM-1 to modulate adhesion and migration of tumor cells.
N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression.
Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.
NMT1 inhibition modulates breast cancer progression through stress-triggered JNK pathway.
Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model.
N-Myristoyltransferase 1 interacts with calnexin at the endoplasmic reticulum.
Regulation of co- and post-translational myristoylation of proteins during apoptosis: interplay of N-myristoyltransferases and caspases.
Beauchamp E, Gamma JM, Cromwell CR, Moussa EW, Pain R, Kostiuk MA, Acevedo-Morantes C, Iyer A, Yap M, Vincent KM, Postovit LM, Julien O, Hubbard BP, Mackey JR, Berthiaume LG
Journal of translational medicine 2024 May 7;22(1):431
Journal of translational medicine 2024 May 7;22(1):431
Series of Desloratadine Platinum(IV) Hybrids Displaying Potent Antimetastatic Competence by Inhibiting Epithelial-Mesenchymal Transition and Arousing Immune Response.
Zhang M, Chen Y, Liu Z, Liu M, Wang Q
Journal of medicinal chemistry 2024 Feb 8;67(3):2031-2048
Journal of medicinal chemistry 2024 Feb 8;67(3):2031-2048
NMT1 sustains ICAM-1 to modulate adhesion and migration of tumor cells.
Wang H, Xu X, Wang Y, Xue X, Guo W, Guo S, Qiu S, Cui J, Qiao Y
Cellular signalling 2023 Sep;109:110739
Cellular signalling 2023 Sep;109:110739
N-myristoyltransferase-1 deficiency blocks myristoylation of LAMTOR1 and inhibits bladder cancer progression.
Sun Y, Guan Z, Sheng Q, Duan W, Zhao H, Zhou J, Deng Q, Pei X
Cancer letters 2022 Mar 31;529:126-138
Cancer letters 2022 Mar 31;529:126-138
Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.
Božič J, Motaln H, Janež AP, Markič L, Tripathi P, Yamoah A, Aronica E, Lee YB, Heilig R, Fischer R, Thompson AJ, Goswami A, Rogelj B
Brain : a journal of neurology 2022 Apr 18;145(2):684-699
Brain : a journal of neurology 2022 Apr 18;145(2):684-699
NMT1 inhibition modulates breast cancer progression through stress-triggered JNK pathway.
Deng L, Gao X, Liu B, He X, Xu J, Qiang J, Wu Q, Liu S
Cell death & disease 2018 Nov 16;9(12):1143
Cell death & disease 2018 Nov 16;9(12):1143
Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model.
Díaz B, Ostapoff KT, Toombs JE, Lo J, Bonner MY, Curatolo A, Adsay V, Brekken RA, Arbiser JL
Oncotarget 2016 Aug 9;7(32):51569-51580
Oncotarget 2016 Aug 9;7(32):51569-51580
N-Myristoyltransferase 1 interacts with calnexin at the endoplasmic reticulum.
Dudek E, Millott R, Liu WX, Beauchamp E, Berthiaume LG, Michalak M
Biochemical and biophysical research communications 2015 Dec 25;468(4):889-93
Biochemical and biophysical research communications 2015 Dec 25;468(4):889-93
Regulation of co- and post-translational myristoylation of proteins during apoptosis: interplay of N-myristoyltransferases and caspases.
Perinpanayagam MA, Beauchamp E, Martin DD, Sim JY, Yap MC, Berthiaume LG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Feb;27(2):811-21
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Feb;27(2):811-21
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 11546-1-AP(NMT1 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using NMT1 antibody 11546-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 11546-1-AP(NMT1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue