Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- HPA020728 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA020728, RRID:AB_1844416
- Product name
- Anti-AASS
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human AASS, Gene description: aminoadipate-semialdehyde synthase, Alternative Gene Names: LKRSDH, LORSDH, Validated applications: ICC, IHC, WB, Uniprot ID: Q9UDR5, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Rescue of glutaric aciduria type I in mice by liver-directed therapies
The lysine catabolite saccharopine impairs development by disrupting mitochondrial homeostasis
Genetic basis of hyperlysinemia
Barzi M, Johnson C, Chen T, Rodriguiz R, Hemmingsen M, Gonzalez T, Rosales A, Beasley J, Peck C, Ma Y, Stiles A, Wood T, Maeso-Diaz R, Diehl A, Young S, Everitt J, Wetsel W, Lagor W, Bissig-Choisat B, Asokan A, El-Gharbawy A, Bissig K
Science Translational Medicine 2023;15(692)
Science Translational Medicine 2023;15(692)
The lysine catabolite saccharopine impairs development by disrupting mitochondrial homeostasis
Zhou J, Wang X, Wang M, Chang Y, Zhang F, Ban Z, Tang R, Gan Q, Wu S, Guo Y, Zhang Q, Wang F, Zhao L, Jing Y, Qian W, Wang G, Guo W, Yang C
Journal of Cell Biology 2019;218(2):580-597
Journal of Cell Biology 2019;218(2):580-597
Genetic basis of hyperlysinemia
Houten S, te Brinke H, Denis S, Ruiter J, Knegt A, de Klerk J, Augoustides-Savvopoulou P, Häberle J, Baumgartner M, Coşkun T, Zschocke J, Sass J, Poll-The B, Wanders R, Duran M
Orphanet Journal of Rare Diseases 2013;8(1):57
Orphanet Journal of Rare Diseases 2013;8(1):57
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human liver and skeletal muscle tissues using HPA020728 antibody. Corresponding AASS RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol