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- Antigen structure
- References [12]
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- Product number
- 14242-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14242-1-AP, RRID:AB_2164365
- Product name
- PIAS4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PIAS4 antibody (Cat. #14242-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references NSMCE2 dispensability in mouse spermatogenesis suggests functional redundancy within the meiotic repair network.
PIASy deficiency mitigates thoracic aortic aneurysm formation via the TGF-β/Smad2/3 pathway.
Coilin and SUMOylation influence PARP1 dynamics and the DNA damage response.
MITF regulates the subcellular location of HIF1α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
CBX4 Regulates Long-Form Thymic Stromal Lymphopoietin-mediated Airway Inflammation through SUMOylation in House Dust Mite-induced Asthma.
Blockade of CBX4-mediated β-catenin SUMOylation attenuates airway epithelial barrier dysfunction in asthma.
Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.
Identification of proximal SUMO-dependent interactors using SUMO-ID.
DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program.
Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA.
Protein inhibitor of activated STAT, PIASy regulates α-smooth muscle actin expression by interacting with E12 in mesangial cells.
Qin Z, Xiong Q, Wang M, Fang Y, Fan Q, Ma B, Gao Y, Cheng M, Cao Y, Zhang Y
Frontiers in cell and developmental biology 2026;14:1751806
Frontiers in cell and developmental biology 2026;14:1751806
PIASy deficiency mitigates thoracic aortic aneurysm formation via the TGF-β/Smad2/3 pathway.
Shen D, Zheng H, Shao K, Zhu J, Hou Y, Ding Y
Journal of thoracic disease 2025 May 30;17(5):3400-3409
Journal of thoracic disease 2025 May 30;17(5):3400-3409
Coilin and SUMOylation influence PARP1 dynamics and the DNA damage response.
Tucker SK, Seale BC, Brown DT, Hebert MD
Journal of cell science 2025 May 15;138(10)
Journal of cell science 2025 May 15;138(10)
MITF regulates the subcellular location of HIF1α through SUMOylation to promote the invasion and metastasis of daughter cells derived from polyploid giant cancer cells.
Zheng M, Tian S, Zhou X, Yan M, Zhou M, Yu Y, Zhang Y, Wang X, Li N, Ren L, Zhang S
Oncology reports 2024 May;51(5)
Oncology reports 2024 May;51(5)
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.
Jin S, He X, Ma L, Zhuang Z, Wang Y, Lin M, Cai S, Wei L, Wang Z, Zhao Z, Wu Y, Sun L, Li C, Xie W, Zhao Y, Songyang Z, Peng K, Zhao J, Cui J
Nature communications 2022 Sep 3;13(1):5204
Nature communications 2022 Sep 3;13(1):5204
CBX4 Regulates Long-Form Thymic Stromal Lymphopoietin-mediated Airway Inflammation through SUMOylation in House Dust Mite-induced Asthma.
Liang S, Zhou Z, Zhou Z, Liu J, Huang W, Dong H, Zou F, Zhao H, Yu C, Cai S
American journal of respiratory cell and molecular biology 2022 Jun;66(6):648-660
American journal of respiratory cell and molecular biology 2022 Jun;66(6):648-660
Blockade of CBX4-mediated β-catenin SUMOylation attenuates airway epithelial barrier dysfunction in asthma.
Liang S, Zhou Z, Zhou Z, Liang J, Lin W, Zhang C, Zhou C, Zhao H, Meng X, Zou F, Yu C, Cai S
International immunopharmacology 2022 Dec;113(Pt A):109333
International immunopharmacology 2022 Dec;113(Pt A):109333
Hengshun Aromatic Vinegar Ameliorates Vascular Endothelial Injury via Regulating PKCζ-Mediated Oxidative Stress and Apoptosis.
Li X, Gao M, Zhu S, Yin L, Zhang B, Qi Y, Zhao Y, Yu Y, Xu L
Frontiers in nutrition 2021;8:635232
Frontiers in nutrition 2021;8:635232
Identification of proximal SUMO-dependent interactors using SUMO-ID.
Barroso-Gomila O, Trulsson F, Muratore V, Canosa I, Merino-Cacho L, Cortazar AR, Pérez C, Azkargorta M, Iloro I, Carracedo A, Aransay AM, Elortza F, Mayor U, Vertegaal ACO, Barrio R, Sutherland JD
Nature communications 2021 Nov 18;12(1):6671
Nature communications 2021 Nov 18;12(1):6671
DPPA2/4 and SUMO E3 ligase PIAS4 opposingly regulate zygotic transcriptional program.
Yan YL, Zhang C, Hao J, Wang XL, Ming J, Mi L, Na J, Hu X, Wang Y
PLoS biology 2019 Jun;17(6):e3000324
PLoS biology 2019 Jun;17(6):e3000324
Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA.
Despras E, Sittewelle M, Pouvelle C, Delrieu N, Cordonnier AM, Kannouche PL
Nature communications 2016 Nov 4;7:13326
Nature communications 2016 Nov 4;7:13326
Protein inhibitor of activated STAT, PIASy regulates α-smooth muscle actin expression by interacting with E12 in mesangial cells.
Torikoshi K, Abe H, Matsubara T, Hirano T, Ohshima T, Murakami T, Araki M, Mima A, Iehara N, Fukatsu A, Kita T, Arai H, Doi T
PloS one 2012;7(7):e41186
PloS one 2012;7(7):e41186
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PIAS4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PIAS4. This antibody recognizes human,mouse,rat antigen. The PIAS4 antibody has been validated for the following applications: ELISA, WB analysis.
