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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- ABIN1673691 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein Inhibitor of Activated STAT, 4 (PIAS4) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the C-terminus of human PIAS4, identical to the related mouse and rat sequences.Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.
The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis.
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.
Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP
Nature 2009 Dec 17;462(7275):935-9
Nature 2009 Dec 17;462(7275):935-9
The E3 SUMO ligase PIASy is a regulator of cellular senescence and apoptosis.
Bischof O, Schwamborn K, Martin N, Werner A, Sustmann C, Grosschedl R, Dejean A
Molecular cell 2006 Jun 23;22(6):783-94
Molecular cell 2006 Jun 23;22(6):783-94
PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies.
Sachdev S, Bruhn L, Sieber H, Pichler A, Melchior F, Grosschedl R
Genes & development 2001 Dec 1;15(23):3088-103
Genes & development 2001 Dec 1;15(23):3088-103
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