Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS7771 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PAX4 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PAX4.
- Description
- Pax-4 (paired box gene 4) protein influences normal differentiation of insulin-producing beta cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet ÉÇ cell lines MIN6, ÉÇ TC, and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80% identical to the deduced mouse Pax-4 protein.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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