BS7771

antibody from Bioworld Technology, Inc
Targeting: PAX4 MODY9
Provider product page for BS7771
Western blot
Immunohistochemistry

Antibody data

Product number
BS7771 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PAX4 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PAX4.
Description
Pax-4 (paired box gene 4) protein influences normal differentiation of insulin-producing beta cells and influences normal pancreatic islet development. Pax-4 protein is a transcriptional repressor that binds to a common cis element in the Glucagon, insulin and Somatostatin promoters. Mouse Pax-4 transcript is present in pancreatic islets, and the islet ÉÇ cell lines MIN6, ÉÇ TC, and NIT1. Differentiation of endoderm-derived endocrine pancreas is mediated through Pax-4 and Pax-6. Pax-4 may act as a Pax-6 repressor due to the competition for binding sites and lower transactivation potential of Pax-4. The human Pax-4 gene encodes a deduced 350 amino acid protein that is 80% identical to the deduced mouse Pax-4 protein.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PAX4 protein structure - BS7771 shown in red.