BS2295

antibody from Bioworld Technology, Inc
Targeting: POU3F1 OCT6, OTF6, SCIP
Provider product page for BS2295

Antibody data

Product number
BS2295 - Provider product page
Provider
Bioworld Technology, Inc
Proper citation
Bioworld Technology Cat#BS2295, RRID:AB_1662236
Product name
Oct 6 (A332) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 300-350 of Human Oct-6.
Description
POU homeodomain proteins are transcriptional regulators that function in various developmental processes (e.g. cell division, differentiation, specification and survival of specific cell types) and participate in the determination of cell fate. The 45 kDa POU transcription factor Oct-6 (also designated SCIP and Tst-1) is expressed by late embryonic Schwann cells of the peripheral nervous system and is also expressed by nonmyelinating Schwann cells in adults. Oct-6 is strongly upregulated in promyelin cells because it is required for the timely differentiation of promyelin cells into myelinating cells. Oct-6 functions during myelination and is required for the proper downregulation of its own gene when myelination proceeds. c-Myc can act synergistically with the POU domain of Oct-6 to produce myelin disease pathogenesis in the mammalian central nervous system.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
POU3F1 protein structure - BS2295 shown in red.