26989-1-AP

antibody from Proteintech Group

Targeting: RRAGC FLJ13311, GTR2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

26989-1-AP

Provider

Proteintech Group

Product name

RRAGC antibody

Antibody type

Polyclonal

Description

KD/KO validated RRAGC antibody (Cat. #26989-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

De novo missense variants in RRAGC lead to a fatal mTORopathy of early childhood.

Reijnders MRF, Seibt A, Brugger M, Lamers IJC, Ott T, Klaas O, Horváth J, Rose AMS, Craghill IM, Brunet T, Graf E, Mayerhanser K, Hellebrekers D, Pauck D, Neuen-Jacob E, Rodenburg RJT, Wieczorek D, Klee D, Mayatepek E, Driessen G, Bindermann R, Averdunk L, Lohmeier K, Sinnema M, Stegmann APA, Roepman R, Poulter JA, Distelmaier F
Genetics in medicine : official journal of the American College of Medical Genetics 2023 Jul;25(7):100838

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Inosine enhances tumor mitochondrial respiration by inducing Rag GTPases and nascent protein synthesis under nutrient starvation.

Li MX, Wu XT, Jing WQ, Hou WK, Hu S, Yan W
Cell death & disease 2023 Aug 2;14(8):492

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KAT7-mediated CANX (calnexin) crotonylation regulates leucine-stimulated MTORC1 activity.

Yan G, Li X, Zheng Z, Gao W, Chen C, Wang X, Cheng Z, Yu J, Zou G, Farooq MZ, Zhu X, Zhu W, Zhong Q, Yan X
Autophagy 2022 Dec;18(12):2799-2816