Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14820-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14820-1-AP, RRID:AB_2232549
- Product name
- GPR37/Pael-R antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GPR37/Pael-R antibody (Cat. #14820-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Intranasal administration of recombinant prosaposin attenuates neuronal apoptosis through GPR37/PI3K/Akt/ASK1 pathway in MCAO rats.
GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway.
Chlorogenic acid enhances alveolar macrophages phagocytosis in acute respiratory distress syndrome by activating G protein-coupled receptor 37 (GPR 37).
Osteocalcin Alleviates Lipopolysaccharide-Induced Acute Inflammation via Activation of GPR37 in Macrophages.
Glio- and neuro-protection by prosaposin is mediated by orphan G-protein coupled receptors GPR37L1 and GPR37.
Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6.
Systematic protein-protein interaction mapping for clinically relevant human GPCRs.
GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability.
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.
Yu J, Li J, Matei N, Wang W, Tang L, Pang J, Li X, Fang L, Tang J, Zhang JH, Yan M
Experimental neurology 2024 Mar;373:114656
Experimental neurology 2024 Mar;373:114656
GPR37 promotes colorectal cancer liver metastases by enhancing the glycolysis and histone lactylation via Hippo pathway.
Zhou J, Xu W, Wu Y, Wang M, Zhang N, Wang L, Feng Y, Zhang T, Wang L, Mao A
Oncogene 2023 Nov;42(45):3319-3330
Oncogene 2023 Nov;42(45):3319-3330
Chlorogenic acid enhances alveolar macrophages phagocytosis in acute respiratory distress syndrome by activating G protein-coupled receptor 37 (GPR 37).
He F, Gao F, Cai N, Jiang M, Wu C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154474
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Dec;107:154474
Osteocalcin Alleviates Lipopolysaccharide-Induced Acute Inflammation via Activation of GPR37 in Macrophages.
Qian Z, Liu C, Li H, Yang H, Wu J, Liu J, Li Y, Chen X, Xu J, Li X
Biomedicines 2022 Apr 27;10(5)
Biomedicines 2022 Apr 27;10(5)
Glio- and neuro-protection by prosaposin is mediated by orphan G-protein coupled receptors GPR37L1 and GPR37.
Liu B, Mosienko V, Vaccari Cardoso B, Prokudina D, Huentelman M, Teschemacher AG, Kasparov S
Glia 2018 Nov;66(11):2414-2426
Glia 2018 Nov;66(11):2414-2426
Parkinson's disease-associated receptor GPR37 is an ER chaperone for LRP6.
Berger BS, Acebron SP, Herbst J, Koch S, Niehrs C
EMBO reports 2017 May;18(5):712-725
EMBO reports 2017 May;18(5):712-725
Systematic protein-protein interaction mapping for clinically relevant human GPCRs.
Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gandía J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, Morató X, Otasek D, Kobayashi H, Menendez J, Auerbach D, Angers S, Pržulj N, Bouvier M, Babu M, Ciruela F, Jockers R, Jurisica I, Stagljar I
Molecular systems biology 2017 Mar 15;13(3):918
Molecular systems biology 2017 Mar 15;13(3):918
GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability.
Lundius EG, Vukojevic V, Hertz E, Stroth N, Cederlund A, Hiraiwa M, Terenius L, Svenningsson P
The Journal of biological chemistry 2014 Feb 21;289(8):4660-73
The Journal of biological chemistry 2014 Feb 21;289(8):4660-73
GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin.
Meyer RC, Giddens MM, Schaefer SA, Hall RA
Proceedings of the National Academy of Sciences of the United States of America 2013 Jun 4;110(23):9529-34
Proceedings of the National Academy of Sciences of the United States of America 2013 Jun 4;110(23):9529-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The GPR37/Pael-R antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GPR37/Pael-R. This antibody recognizes human,mouse,rat antigen. The GPR37/Pael-R antibody has been validated for the following applications: ELISA, WB analysis.