Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB4493 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB4493, RRID:AB_1575265
- Product name
- GPR37 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of GPR37.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila.
CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin.
Yang Y, Nishimura I, Imai Y, Takahashi R, Lu B
Neuron 2003 Mar 27;37(6):911-24
Neuron 2003 Mar 27;37(6):911-24
CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.
Imai Y, Soda M, Hatakeyama S, Akagi T, Hashikawa T, Nakayama KI, Takahashi R
Molecular cell 2002 Jul;10(1):55-67
Molecular cell 2002 Jul;10(1):55-67
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin.
Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, Takahashi R
Cell 2001 Jun 29;105(7):891-902
Cell 2001 Jun 29;105(7):891-902
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of GPR37 polyclonal antibody (Cat # PAB4493) in mouse brain tissue lysate . GPR37 (arrow) was detected using the purified GPR37 polyclonal antibody (Cat # PAB4493) .
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with GPR37 polyclonal antibody (Cat # PAB4493) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated . HC = hepatocarcinoma .
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)