Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 14774-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14774-1-AP, RRID:AB_2120339
- Product name
- HNRNPH1 antibody
- Antibody type
- Polyclonal
- Description
- HNRNPH1 antibody (Cat. #14774-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HnRNP H1 binds to nucleocapsid protein and potential guanine-quadruplex site of viral RNA to promote PRRSV-2 proliferation.
DNMT2 inhibits anaplastic thyroid cancer progression by downregulating 5'tiRNA(Gly-GCC) production.
Gene Therapy with Enterovirus 3 C Protease: A Promising Strategy for Various Solid Tumors.
hnRNPH1 maintains mitochondrial homeostasis by establishing NRF1/DRP1 retrograde signaling under mitochondrial stress.
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer.
HNRNPH1 stabilizes FLOT2 mRNA in a non-canonical m6A-dependent manner to promote malignant progression in nasopharyngeal carcinoma.
SUN5, a testis-specific nuclear membrane protein, participates in recruitment and export of nuclear mRNA in spermatogenesis.
Phosphoproteome analysis of the crosstalk between sumoylation and phosphorylation in mouse spermatocytes.
C9orf72 Hexanucleotide Repeat Expansion-Related Neuropathology Is Attenuated by Nasal Rifampicin in Mice.
Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression.
HnRNP F and hnRNP H1 regulate mRNA stability of amyloid precursor protein.
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Corrigendum to article "Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation''.
5' UTR variants in the quantitative trait gene Hnrnph1 support reduced 5' UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity.
Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.
Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
Zhang L, Jing H, Song Y, Zhao P, Zhang Z, Duan E, Liu J, Li H
Research in veterinary science 2026 Jul;206:106188
Research in veterinary science 2026 Jul;206:106188
DNMT2 inhibits anaplastic thyroid cancer progression by downregulating 5'tiRNA(Gly-GCC) production.
Zhou R, Li B, Cao M, Wu Z, Xia F, Li X
Cell death & disease 2026 Feb 21;17(1)
Cell death & disease 2026 Feb 21;17(1)
Gene Therapy with Enterovirus 3 C Protease: A Promising Strategy for Various Solid Tumors.
Yang X, Li W, Yang S, Wang Z, Yin J, Zhang W, Tao H, Li S, Guo X, Dai Q, Zhu W, Li Y, Yan X, Luo C, Li J, Ren S, Wang P, Shao Y, Luo Y, Li Z, Yang J, Chang Z, Cao R, Li S, Zhong W
Nature communications 2025 May 8;16(1):4298
Nature communications 2025 May 8;16(1):4298
hnRNPH1 maintains mitochondrial homeostasis by establishing NRF1/DRP1 retrograde signaling under mitochondrial stress.
Zhao L, Zou X, Deng J, Sun B, Li Y, Zhao L, Zhao H, Zhang X, Yuan X, Zhao X, Zou F
Cell death and differentiation 2025 Jan;32(1):118-133
Cell death and differentiation 2025 Jan;32(1):118-133
PTK6 drives HNRNPH1 phase separation to activate autophagy and suppress apoptosis in colorectal cancer.
Chen B, Liu B, Chen J, Li W, Ma N, Liu J, Fan R, Hu Q, Song H, Xu Y, Jiang T, Song J
Autophagy 2025 Aug;21(8):1680-1699
Autophagy 2025 Aug;21(8):1680-1699
HNRNPH1 stabilizes FLOT2 mRNA in a non-canonical m6A-dependent manner to promote malignant progression in nasopharyngeal carcinoma.
Li Q, Liu J, Zeng C, Qin D, Zhang Z, Lv Q, Li J, Huang W
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2279-2295
Cellular oncology (Dordrecht, Netherlands) 2024 Dec;47(6):2279-2295
SUN5, a testis-specific nuclear membrane protein, participates in recruitment and export of nuclear mRNA in spermatogenesis.
He X, Zhang Y, Mao Z, Liu G, Huang L, Liu X, Su Y, Xing X
Acta biochimica et biophysica Sinica 2024 Aug 6;56(11):1673-1686
Acta biochimica et biophysica Sinica 2024 Aug 6;56(11):1673-1686
Phosphoproteome analysis of the crosstalk between sumoylation and phosphorylation in mouse spermatocytes.
Applebaum N, Chemel S, Matveev S, Pal SS, Sengupta A, Lucas B, Vigodner M
Biochemical and biophysical research communications 2023 Nov 12;681:194-199
Biochemical and biophysical research communications 2023 Nov 12;681:194-199
C9orf72 Hexanucleotide Repeat Expansion-Related Neuropathology Is Attenuated by Nasal Rifampicin in Mice.
Hatanaka Y, Umeda T, Shigemori K, Takeuchi T, Nagai Y, Tomiyama T
Biomedicines 2022 May 6;10(5)
Biomedicines 2022 May 6;10(5)
Selective sorting and secretion of hY4 RNA fragments into extracellular vesicles mediated by methylated YBX1 to promote lung cancer progression.
Li C, Wang W, Sun Y, Ni Y, Qin F, Li X, Wang T, Guo M, Sun G
Journal of experimental & clinical cancer research : CR 2022 Apr 11;41(1):136
Journal of experimental & clinical cancer research : CR 2022 Apr 11;41(1):136
HnRNP F and hnRNP H1 regulate mRNA stability of amyloid precursor protein.
Khan MI, Zhang J, Liu Q
Neuroreport 2021 Jun 9;32(9):824-832
Neuroreport 2021 Jun 9;32(9):824-832
TDP-43 aggregation induced by oxidative stress causes global mitochondrial imbalance in ALS.
Zuo X, Zhou J, Li Y, Wu K, Chen Z, Luo Z, Zhang X, Liang Y, Esteban MA, Zhou Y, Fu XD
Nature structural & molecular biology 2021 Feb;28(2):132-142
Nature structural & molecular biology 2021 Feb;28(2):132-142
Corrigendum to article "Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation''.
Chen R, Liu Y, Zhuang H, Yang B, Hei K, Xiao M, Hou C, Gao H, Zhang X, Jia C, Li L, Li Y, Zhang N
Nucleic acids research 2021 Apr 19;49(7):4199-4202
Nucleic acids research 2021 Apr 19;49(7):4199-4202
5' UTR variants in the quantitative trait gene Hnrnph1 support reduced 5' UTR usage and hnRNP H protein as a molecular mechanism underlying reduced methamphetamine sensitivity.
Ruan QT, Yazdani N, Reed ER, Beierle JA, Peterson LP, Luttik KP, Szumlinski KK, Johnson WE, Ash PEA, Wolozin B, Bryant CD
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9223-9244
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jul;34(7):9223-9244
Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.
Chen R, Liu Y, Zhuang H, Yang B, Hei K, Xiao M, Hou C, Gao H, Zhang X, Jia C, Li L, Li Y, Zhang N
Nucleic acids research 2017 Sep 29;45(17):9947-9959
Nucleic acids research 2017 Sep 29;45(17):9947-9959
Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
Neumann M, Valori CF, Ansorge O, Kretzschmar HA, Munoz DG, Kusaka H, Yokota O, Ishihara K, Ang LC, Bilbao JM, Mackenzie IR
Acta neuropathologica 2012 Nov;124(5):705-16
Acta neuropathologica 2012 Nov;124(5):705-16
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 14774-1-AP(HNRNPH1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 14774-1-AP(HNRNPH1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The HNRNPH1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HNRNPH1. This antibody recognizes human,mouse,rat antigen. The HNRNPH1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.