BS6945

antibody from Bioworld Technology, Inc

Targeting: COL9A1

Western blot (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

BS6945

Provider

Bioworld Technology, Inc

Product name

COL9A1 polyclonal antibody

Antibody type

Polyclonal

Antigen

Recombinant full length Human COL9A1.

Description

The Collagen Type IX protein (also known as Collagen Ï«1 Type IX) is encoded by the COL9A1 gene which possesses two promoter regions and codes for both a long chain Collagen Type IX protein expressed in the cartilage, and a shorter Collagen Type IX protein expressed in the cornea and vitreous. Collagen Type IX forms a heterotrimer with Collagen Ï«2 Type IX and Collagen Ï«3 Type IX. When it is expressed in hyaline cartilage, Collagen Type IX posseses a large N-terminal globular domain (NC4). The COL9A1 gene is also expressed in the human inner ear, and disruption of this gene in mice results in hearing loss, indicating the role of Collagen Type IX in hearing. Mutations in the COL9A1 gene are associated with multiple epiphyseal dysplasia (MED), a chondrodysplasia, in humans. Collagen Type IX is often co-localized with Collagen Type II, and may play a role in the interaction of fibrils between Collagen Type II and Collagen Type IX.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.