Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- M00403 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-NOX4 Rabbit Monoclonal Antibody
- Antibody type
- Monoclonal
- Description
- Monoclonal antibody for NOX4 detection. Host: Rabbit.Size: 100ug/vial. Tested applications: IP, IF, IHC, ICC, WB. Reactive species: Human, Mouse, Rat NOX4 information: Molecular Weight: 66932 MW; Subcellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein . Cell junction, focal adhesion . May localize to plasma membrane and focal adhesions. According to PubMed:15927447, may also localize to the nucleus; Tissue Specificity: Expressed by distal tubular cells in kidney cortex and in endothelial cells (at protein level). Widely expressed. Strongly expressed in kidney and to a lower extent in heart, adipocytes, hepatoma, endothelial cells, skeletal muscle, brain, several brain tumor cell lines and airway epithelial cells.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Antibody clone number
- E-14
- Vial size
- 100ug/vial
- Storage
- At -20°C for one year. Avoid repeated freezing and thawing.
Submitted references AQP3 Promotes the Invasion and Metastasis in Cervical Cancer by Regulating NOX4-derived H(2)O(2) Activation of Syk/PI3K/Akt Signaling Axis.
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Remodeling of the liver fibrosis microenvironment based on nilotinib-loaded multicatalytic nanozymes with boosted antifibrogenic activity.
Nrf2-Dependent Protective Effect of Paeoniflorin on α-Naphthalene Isothiocyanate-Induced Hepatic Injury.
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
The Protective Role of Tanshinone IIA in Silicosis Rat Model via TGF-β1/Smad Signaling Suppression, NOX4 Inhibition and Nrf2/ARE Signaling Activation.
Study of the selenizing Codonopsis pilosula polysaccharides protects RAW264.7 cells from hydrogen peroxide-induced injury.
RAP-8 ameliorates liver fibrosis by modulating cell cycle and oxidative stress.
Inhibition of CPU0213, a Dual Endothelin Receptor Antagonist, on Apoptosis via Nox4-Dependent ROS in HK-2 Cells.
Wang Q, Lin B, Wei H, Wang X, Nie X, Shi Y
Journal of Cancer 2024;15(4):1124-1137
Journal of Cancer 2024;15(4):1124-1137
Inhibition of AT1R/IP3/IP3R-mediated Ca(2+) release protects against calcium oxalate crystals-induced renal oxidative stress.
Hong SY, Yang YY, Wang SG, Qin BL
Chemico-biological interactions 2023 Sep 1;382:110636
Chemico-biological interactions 2023 Sep 1;382:110636
Remodeling of the liver fibrosis microenvironment based on nilotinib-loaded multicatalytic nanozymes with boosted antifibrogenic activity.
Jing H, Ren Y, Zhou Y, Xu M, Krizkova S, Heger Z, Lu Q, Wang S, Liang X, Adam V, Li N
Acta pharmaceutica Sinica. B 2023 Dec;13(12):5030-5047
Acta pharmaceutica Sinica. B 2023 Dec;13(12):5030-5047
Nrf2-Dependent Protective Effect of Paeoniflorin on α-Naphthalene Isothiocyanate-Induced Hepatic Injury.
Mao L, Chen J, Cheng K, Dou Z, Leavenworth JD, Yang H, Xu D, Luo L
The American journal of Chinese medicine 2022;50(5):1331-1348
The American journal of Chinese medicine 2022;50(5):1331-1348
Purple Sweet Potato Color Attenuates Kidney Damage by Blocking VEGFR2/ROS/NLRP3 Signaling in High-Fat Diet-Treated Mice.
Zheng GH, Shan Q, Mu JJ, Wang YJ, Zhang ZF, Fan SH, Hu B, Li MQ, Xie J, Chen P, Wu DM, Lu J, Zheng YL
Oxidative medicine and cellular longevity 2019;2019:5189819
Oxidative medicine and cellular longevity 2019;2019:5189819
The Protective Role of Tanshinone IIA in Silicosis Rat Model via TGF-β1/Smad Signaling Suppression, NOX4 Inhibition and Nrf2/ARE Signaling Activation.
Feng F, Cheng P, Zhang H, Li N, Qi Y, Wang H, Wang Y, Wang W
Drug design, development and therapy 2019;13:4275-4290
Drug design, development and therapy 2019;13:4275-4290
Study of the selenizing Codonopsis pilosula polysaccharides protects RAW264.7 cells from hydrogen peroxide-induced injury.
Qin T, Ren Z, Liu X, Luo Y, Long Y, Peng S, Chen S, Zhang J, Ma Y, Li J, Huang Y
International journal of biological macromolecules 2019 Mar 15;125:534-543
International journal of biological macromolecules 2019 Mar 15;125:534-543
RAP-8 ameliorates liver fibrosis by modulating cell cycle and oxidative stress.
Xu H, Hong S, Yan Z, Zhao Q, Shi Y, Song N, Xie J, Jiang X
Life sciences 2019 Jul 15;229:200-209
Life sciences 2019 Jul 15;229:200-209
Inhibition of CPU0213, a Dual Endothelin Receptor Antagonist, on Apoptosis via Nox4-Dependent ROS in HK-2 Cells.
Li Q, Li J, Shao H, Li XX, Yu F, Xu M
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(1):183-92
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016;39(1):183-92
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Supportive validation
- Submitted by
- Boster Biological Technology (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of paraffin-embedded rat kidney, using NOX4 Antibody.
- Additional image