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- References [13]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 22092-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- IMPDH1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IMPDH1 antibody (Cat. #22092-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Catalytic isoforms of AMP-activated protein kinase differentially regulate IMPDH activity and photoreceptor neuron function.
Inosine monophosphate dehydrogenase intranuclear inclusions are markers of aging and neuronal stress in the human substantia nigra.
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
LncRNA UCA1 Participates in De Novo Synthesis of Guanine Nucleotides in Bladder Cancer by Recruiting TWIST1 to Increase IMPDH1/2.
Characterization of the microenvironment in different immune-metabolism subtypes of cervical cancer with prognostic significance.
IMPDH1, a prognostic biomarker and immunotherapy target that correlates with tumor immune microenvironment in pan-cancer and hepatocellular carcinoma.
Nuclear IMPDH Filaments in Human Gliomas.
Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line.
IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors.
ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis.
Reference standards for the detection of anti-mitochondrial and anti-rods/rings autoantibodies.
Loukoumasomes Are Distinct Subcellular Structures from Rods and Rings and Are Structurally Associated with MAP2 and the Nuclear Envelope in Retinal Cells.
Characterisation of inosine monophosphate dehydrogenase expression during retinal development: differences between variants and isoforms.
Lee TJ, Sasaki Y, Ruzycki PA, Ban N, Lin JB, Wu HT, Santeford A, Apte RS
JCI insight 2024 Jan 16;9(4)
JCI insight 2024 Jan 16;9(4)
Inosine monophosphate dehydrogenase intranuclear inclusions are markers of aging and neuronal stress in the human substantia nigra.
Woulfe J, Munoz DG, Gray DA, Jinnah HA, Ivanova A
Neurobiology of aging 2024 Feb;134:43-56
Neurobiology of aging 2024 Feb;134:43-56
The Role of Purine Metabolism-Related Genes PPAT and IMPDH1 in the Carcinogenesis of Intrahepatic Cholangiocarcinoma Based on Metabonomic and Bioinformatic Analyses.
Liu CJ, Ma ZZ, Gong WZ, Mao XH, Wen HQ, Wang XH
Journal of oncology 2023;2023:5141836
Journal of oncology 2023;2023:5141836
LncRNA UCA1 Participates in De Novo Synthesis of Guanine Nucleotides in Bladder Cancer by Recruiting TWIST1 to Increase IMPDH1/2.
Liu SS, Li JS, Xue M, Wu WJ, Li X, Chen W
International journal of biological sciences 2023;19(8):2599-2612
International journal of biological sciences 2023;19(8):2599-2612
Characterization of the microenvironment in different immune-metabolism subtypes of cervical cancer with prognostic significance.
Lai W, Liao J, Li X, Liang P, He L, Huang K, Liang X, Wang Y
Frontiers in genetics 2023;14:1067666
Frontiers in genetics 2023;14:1067666
IMPDH1, a prognostic biomarker and immunotherapy target that correlates with tumor immune microenvironment in pan-cancer and hepatocellular carcinoma.
Liu C, Zhang W, Zhou X, Liu L
Frontiers in immunology 2022;13:983490
Frontiers in immunology 2022;13:983490
Nuclear IMPDH Filaments in Human Gliomas.
Ahangari N, Munoz DG, Coulombe J, Gray DA, Engle EC, Cheng L, Woulfe J
Journal of neuropathology and experimental neurology 2021 Oct 26;80(10):944-954
Journal of neuropathology and experimental neurology 2021 Oct 26;80(10):944-954
Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line.
Kollareddy M, Martinez LA
Cells 2021 Apr 2;10(4)
Cells 2021 Apr 2;10(4)
IMPDH1/YB-1 Positive Feedback Loop Assembles Cytoophidia and Represents a Therapeutic Target in Metastatic Tumors.
Ruan H, Song Z, Cao Q, Ni D, Xu T, Wang K, Bao L, Tong J, Xiao H, Xiao W, Cheng G, Xiong Z, Liang H, Liu D, Wang L, Olivier T, Jane BH, Yang H, Zhang X, Chen K
Molecular therapy : the journal of the American Society of Gene Therapy 2020 May 6;28(5):1299-1313
Molecular therapy : the journal of the American Society of Gene Therapy 2020 May 6;28(5):1299-1313
ERK2 Phosphorylates PFAS to Mediate Posttranslational Control of De Novo Purine Synthesis.
Ali ES, Sahu U, Villa E, O'Hara BP, Gao P, Beaudet C, Wood AW, Asara JM, Ben-Sahra I
Molecular cell 2020 Jun 18;78(6):1178-1191.e6
Molecular cell 2020 Jun 18;78(6):1178-1191.e6
Reference standards for the detection of anti-mitochondrial and anti-rods/rings autoantibodies.
Calise SJ, Zheng B, Hasegawa T, Satoh M, Isailovic N, Ceribelli A, Andrade LEC, Boylan K, Cavazzana I, Fritzler MJ, de la Torre IG, Hiepe F, Kohl K, Selmi C, Shoenfeld Y, Tincani A, Chan EKL, IUIS Autoantibody Standardization Committee
Clinical chemistry and laboratory medicine 2018 Sep 25;56(10):1789-1798
Clinical chemistry and laboratory medicine 2018 Sep 25;56(10):1789-1798
Loukoumasomes Are Distinct Subcellular Structures from Rods and Rings and Are Structurally Associated with MAP2 and the Nuclear Envelope in Retinal Cells.
Noble JW, Hunter DV, Roskelley CD, Chan EK, Mills J
PloS one 2016;11(10):e0165162
PloS one 2016;11(10):e0165162
Characterisation of inosine monophosphate dehydrogenase expression during retinal development: differences between variants and isoforms.
Gunter JH, Thomas EC, Lengefeld N, Kruger SJ, Worton L, Gardiner EM, Jones A, Barnett NL, Whitehead JP
The international journal of biochemistry & cell biology 2008;40(9):1716-28
The international journal of biochemistry & cell biology 2008;40(9):1716-28
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 22092-1-AP(IMPDH1 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IMPDH1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IMPDH1. This antibody recognizes human, mouse, rat antigen. The IMPDH1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
