FAB118P

antibody from R&D Systems

Targeting: IL18RAP AcPL, CD218b

Flow cytometry (Recommended by provider)

Antibody Data

Product number

FAB118P

Provider

R&D Systems

Product name

Anti-Human IL-18 R beta/IL-1 R7 PE-conjugated Monoclonal Antibody (Clone 132029)

Antibody type

Monoclonal

Antigen

Mouse myeloma cell line NS0-derived recombinant human IL‑18 Rβ/IL‑1 R7, Met1-Arg356

Description

Protein A or G purified from hybridoma culture supernatant

Reactivity

Human

Host

Mouse

Conjugate

Yellow dye

Antigen sequence

O95256


Isotype

IgG

Vial size

100 Tests

References

Submitted references

Regulatory Dendritic Cells Restrain NK Cell IFN-γ Production through Mechanisms Involving NKp46, IL-10, and MHC Class I-Specific Inhibitory Receptors.

Spallanzani RG, Torres NI, Avila DE, Ziblat A, Iraolagoitia XL, Rossi LE, Domaica CI, Fuertes MB, Rabinovich GA, Zwirner NW
Journal of immunology (Baltimore, Md. : 1950) 2015 Sep 1;195(5):2141-8

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Interleukin-18 produced by bone marrow-derived stromal cells supports T-cell acute leukaemia progression.

Uzan B, Poglio S, Gerby B, Wu CL, Gross J, Armstrong F, Calvo J, Cahu X, Deswarte C, Dumont F, Passaro D, Besnard-Guérin C, Leblanc T, Baruchel A, Landman-Parker J, Ballerini P, Baud V, Ghysdael J, Baleydier F, Porteu F, Pflumio F
EMBO molecular medicine 2014 Jun;6(6):821-34

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Increased expression of interleukin-18 receptor in blood cells of subjects with mild cognitive impairment and Alzheimer's disease.

Salani F, Ciaramella A, Bizzoni F, Assogna F, Caltagirone C, Spalletta G, Bossù P
Cytokine 2013 Feb;61(2):360-3

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Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis.

de Jager W, Vastert SJ, Beekman JM, Wulffraat NM, Kuis W, Coffer PJ, Prakken BJ
Arthritis and rheumatism 2009 Sep;60(9):2782-93