Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS2817 - Provider product page
- Provider
- Bioworld Technology, Inc
- Proper citation
- Bioworld Technology Cat#BS2817, RRID:AB_1662217
- Product name
- MEL 1B R (V39) polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids N-terminus of Human MEL-1B-R.
- Description
- The melatonin receptors, MEL-1A-R and MEL-1B-R, are members of the superfamily of guanine nucleotide-binding regulatory protein (G protein)-coupled receptors. The melatonin receptors are activated by the hormone melatonin (Mel), which is secreted by the pineal gland at night as part of the circadian clock. MEL-1A-R, a 37 kD protein, is thought to be involved in pacing the biological clock. However, both MEL-1A-R and MEL-1B-R are implicated in controlling cellular growth in response to melatonin. MEL-1B-R is an integral membrane protein expressed in retina and less in brain and hippocampus. Functional studies of NIH/3T3 cells stably expressing the MEL-1B-R melatonin receptor indicate that it is coupled to inhibition of adenylyl cyclase.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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