Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11540-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11540-1-AP, RRID:AB_2165035
- Product name
- PLAGL2 antibody
- Antibody type
- Polyclonal
- Description
- PLAGL2 antibody (Cat. #11540-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exosome-mediated Delivery of miR-519e-5p Promotes Malignant Tumor Phenotype and CD8+ T-Cell Exhaustion in Metastatic PTC.
POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression.
METTL14 Regulates PLAGL2/β-Catenin Signaling Axis to Promote the Development of Nonsmall Cell Lung Cancer.
PLAGL2 induces nucleus pulposus cell apoptosis via regulating RASSF5 expression and thus accelerates intervertebral disc degeneration.
PLAGL2 promotes Snail expression and gastric cancer progression via UCA1/miR-145-5p/YTHDF1 axis.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
PLAGL2 increases adriamycin resistance and EMT in breast cancer cells by activating the Wnt pathway.
Overexpression of GATA5 Inhibits Prostate Cancer Progression by Regulating PLAGL2 via the FAK/PI3K/AKT Pathway.
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness.
Pleomorphic adenoma gene-like 2 regulates expression of the p53 family member, p73, and induces cell cycle block and apoptosis in human promonocytic U937 cells.
Modulation of PLAGL2 transactivation by positive cofactor 2 (PC2), a component of the ARC/Mediator complex.
Li G, Chen W, Jiang K, Huang J, Zhong J, Liu X, Wei T, Gong R, Li Z, Zhu J, Shi H, Lei J
The Journal of clinical endocrinology and metabolism 2024 May 17;109(6):1601-1617
The Journal of clinical endocrinology and metabolism 2024 May 17;109(6):1601-1617
POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression.
Monno M, Ogiri M, Seishima R, Suzuki Y, Hattori K, Matsui S, Shigeta K, Okabayashi K, Kitagawa Y
Cell biochemistry and function 2024 Mar;42(2):e3989
Cell biochemistry and function 2024 Mar;42(2):e3989
METTL14 Regulates PLAGL2/β-Catenin Signaling Axis to Promote the Development of Nonsmall Cell Lung Cancer.
Zhou Q, Lai X, Gao Y, Chen Q, Xu Y, Liu Y
Journal of oncology 2023;2023:4738586
Journal of oncology 2023;2023:4738586
PLAGL2 induces nucleus pulposus cell apoptosis via regulating RASSF5 expression and thus accelerates intervertebral disc degeneration.
Zhu G, Yang X, Zhou W, Lian X, Hao Y
Experimental cell research 2023 Sep 1;430(1):113699
Experimental cell research 2023 Sep 1;430(1):113699
PLAGL2 promotes Snail expression and gastric cancer progression via UCA1/miR-145-5p/YTHDF1 axis.
Chen W, He Q, Liu J, Li N, Xiao K, Chen H
Carcinogenesis 2023 Jun 24;44(4):328-340
Carcinogenesis 2023 Jun 24;44(4):328-340
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
PLAGL2 increases adriamycin resistance and EMT in breast cancer cells by activating the Wnt pathway.
Li Y, Liu R, Han X, Xu W, Liu Y
Genes & genomics 2023 Jan;45(1):49-57
Genes & genomics 2023 Jan;45(1):49-57
Overexpression of GATA5 Inhibits Prostate Cancer Progression by Regulating PLAGL2 via the FAK/PI3K/AKT Pathway.
Wang Q, Liu Z, Zhai G, Yu X, Ke S, Shao H, Guo J
Cancers 2022 Apr 21;14(9)
Cancers 2022 Apr 21;14(9)
Increased miR-214 expression suppresses cell migration and proliferation in Hirschsprung disease by interacting with PLAGL2.
Wu L, Yuan W, Chen J, Zhou Z, Shu Y, Ji J, Liu Z, Tang Q, Zhang X, Shu X
Pediatric research 2019 Oct;86(4):460-470
Pediatric research 2019 Oct;86(4):460-470
PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemness.
Li D, Lin C, Li N, Du Y, Yang C, Bai Y, Feng Z, Su C, Wu R, Song S, Yan P, Chen M, Jain A, Huang L, Zhang Y, Li X
EBioMedicine 2019 Jul;45:124-138
EBioMedicine 2019 Jul;45:124-138
Pleomorphic adenoma gene-like 2 regulates expression of the p53 family member, p73, and induces cell cycle block and apoptosis in human promonocytic U937 cells.
Hanks TS, Gauss KA
Apoptosis : an international journal on programmed cell death 2012 Mar;17(3):236-47
Apoptosis : an international journal on programmed cell death 2012 Mar;17(3):236-47
Modulation of PLAGL2 transactivation by positive cofactor 2 (PC2), a component of the ARC/Mediator complex.
Wezensky SJ, Hanks TS, Wilkison MJ, Ammons MC, Siemsen DW, Gauss KA
Gene 2010 Feb 15;452(1):22-34
Gene 2010 Feb 15;452(1):22-34
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PLAGL2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PLAGL2. This antibody recognizes human, mouse, rat antigen. The PLAGL2 antibody has been validated for the following applications: ELISA, WB analysis.