NBP1-87852
antibody from Novus Biologicals
Targeting: PTGES
MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12
Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [8]
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Validation data
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- Product number
- NBP1-87852 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-87852, RRID:AB_11007086
- Product name
- Rabbit Polyclonal Prostaglandin E Synthase Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Prostaglandin E Synthase antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Ellagitannins from Punica granatum leaves suppress microsomal prostaglandin E synthase-1 expression and induce lung cancer cells to undergo apoptosis.
The COX2 Effector Microsomal PGE2 Synthase 1 is a Regulator of Immunosuppression in Cutaneous Melanoma.
Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression.
Microsomal prostaglandin E synthase-1 protects against Fas-induced liver injury.
Active smoking increases microsomal PGE2-synthase-1/PGE-receptor-4 axis in human abdominal aortic aneurysms.
Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.
Toda K, Ueyama M, Tanaka S, Tsukayama I, Mega T, Konoike Y, Tamenobu A, Bastian F, Akai I, Ito H, Kawakami Y, Takahashi Y, Suzuki-Yamamoto T
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):757-763
Bioscience, biotechnology, and biochemistry 2020 Apr;84(4):757-763
The COX2 Effector Microsomal PGE2 Synthase 1 is a Regulator of Immunosuppression in Cutaneous Melanoma.
Kim SH, Roszik J, Cho SN, Ogata D, Milton DR, Peng W, Menter DG, Ekmekcioglu S, Grimm EA
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Mar 1;25(5):1650-1663
Clinical cancer research : an official journal of the American Association for Cancer Research 2019 Mar 1;25(5):1650-1663
Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression.
Kim SH, Hashimoto Y, Cho SN, Roszik J, Milton DR, Dal F, Kim SF, Menter DG, Yang P, Ekmekcioglu S, Grimm EA
Pigment cell & melanoma research 2016 May;29(3):297-308
Pigment cell & melanoma research 2016 May;29(3):297-308
Microsomal prostaglandin E synthase-1 protects against Fas-induced liver injury.
Yao L, Chen W, Han C, Wu T
American journal of physiology. Gastrointestinal and liver physiology 2016 Jun 1;310(11):G1071-80
American journal of physiology. Gastrointestinal and liver physiology 2016 Jun 1;310(11):G1071-80
Active smoking increases microsomal PGE2-synthase-1/PGE-receptor-4 axis in human abdominal aortic aneurysms.
Dilmé JF, Solà-Villà D, Bellmunt S, Romero JM, Escudero JR, Camacho M, Vila L
Mediators of inflammation 2014;2014:316150
Mediators of inflammation 2014;2014:316150
Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm.
Camacho M, Dilmé J, Solà-Villà D, Rodríguez C, Bellmunt S, Siguero L, Alcolea S, Romero JM, Escudero JR, Martínez-González J, Vila L
Journal of lipid research 2013 Dec;54(12):3506-15
Journal of lipid research 2013 Dec;54(12):3506-15
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Prostaglandin E Synthase Antibody [NBP1-87852] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Prostaglandin E Synthase Antibody [NBP1-87852] - Analysis in human cell lines A-549 and U-251MG. Corresponding RNA-seq data are presented for the same cell lines. Loading control: Anti-GAPDH.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human endometrium shows low expression as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human seminal vesicle shows high expression.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Analysis in human seminal vesicle and pancreas tissues. Corresponding Prostaglandin E Synthase RNA-seq data are presented for the same tissues.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human pancreas shows no positivity in exocrine glandular cells as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human placenta shows strong cytoplasmic positivity in decidual cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human seminal vesicle shows strong membranous and cytoplasmic positivity in glandular cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human testis shows weak to moderate membranous and cytoplasmic positivity in cells in seminiferous ducts.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Prostaglandin E Synthase Antibody [NBP1-87852] - Staining of human urinary bladder shows moderate cytoplasmic positivity in urothelial cells.