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- Antibody Data
- Antigen structure
- References [23]
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- Product number
- 66832-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- NRF1/nuclear respiratory factor 1 antibody
- Antibody type
- Monoclonal
- Description
- NRF1/nuclear respiratory factor 1 antibody (Cat. #66832-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 3C2B8
- Vial size
- 20ul, 150ul
Submitted references Histone Lactylation Couples FSH-Driven Lactate Metabolism to Mitochondrial Biogenesis by Enhancing HDAC4-Mediated Deacetylation of PGC-1α in Granulosa Cells.
Atractylodes macrocephala Koidz. water extract alleviates exercise-induced fatigue by activating mitochondrial biogenesis via the PGC-1α/NRF1/TFAM axis.
A Rsv@HMnO(2)-HA nanozyme for AKI therapy via targeting inflammatory storm and activating SIRT1/PGC-1α to restore mitochondrial homeostasis.
SIRT3-mediated mitochondrial fatty acid oxidation protects against hepatic lipid deposition in fatty liver hemorrhagic syndrome.
HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF-κB/SOD2 Signaling Pathway.
Electrical Vagus Nerve Stimulation Ameliorates Cardiac Ischemia and Reperfusion Injury by Improving Mitochondrial Biogenesis Through the SIRT1/PGC-1α Pathway.
The total extract of Abelmoschus manihot (L.) medic flowers (TEA) mediated Nrf2-TFAM signalling to regulate mitochondrial antioxidant mechanism.
sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2.
Zn(2 +) alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
Sini-Suanzaoren decoction regulates mitochondrial biogenesis mediated by MT-SIRT1 in the treatment of insomnia rats.
NMN improves cardiac function in SIRT3 knockout mice via the SIRT1/PGC-1α pathway.
Boosting energy metabolism and biosynthesis in diverse organisms by a common bacterial salvage lipoylation protein.
Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mousmodel of Alzheimer's disease.
S100A8/A9(hi) neutrophils induce mitochondrial dysfunction and PANoptosis in endothelial cells via mitochondrial complex I deficiency during sepsis.
M6A RNA Methylation-Mediated TUG1 Stability Maintains Mitochondrial Homeostasis during Kidney Aging by Epigenetically Regulating PGC1-α Expression.
NRF1-induced mmu_circ_0001388/hsa_circ_0029470 confers ferroptosis resistance in ischemic acute kidney injury via the miR-193b-3p/TCF4/GPX4 axis.
NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1.
Hydrogen sulfide alleviates heart failure with preserved ejection fraction in mice by targeting mitochondrial abnormalities via PGC-1α.
Efficacy of creatine nitrate supplementation on redox status and mitochondrial function in pectoralis major muscle of preslaughter transported broilers.
Styrax (Liquidambar orientalis Mill.) promotes mitochondrial function and reduces cardiac damage following myocardial ischemic injury: the role of the AMPK-PGC1α signaling pathway.
Zerumbone attenuates the excessive proliferation of keratinocytes in psoriasis mice through regulating NLRP3/NF-κB pathway.
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
Icaritin Attenuates Lipid Accumulation by Increasing Energy Expenditure and Autophagy Regulated by Phosphorylating AMPK.
Wu G, Chen M, Li C, Wei M, Pan Y, He T, Liu Z, Li H, Zhang C, Zhang JQ, Sheng Y, Liu Y, Liu H, Shen M
Research (Washington, D.C.) 2026;9:1045
Research (Washington, D.C.) 2026;9:1045
Atractylodes macrocephala Koidz. water extract alleviates exercise-induced fatigue by activating mitochondrial biogenesis via the PGC-1α/NRF1/TFAM axis.
Ying G, Yu J, Jiao L, Liang J, Wu Z, Pan B, Gao S, Chen S, Lv G
Journal of ethnopharmacology 2026 Mar 25;359:121053
Journal of ethnopharmacology 2026 Mar 25;359:121053
A Rsv@HMnO(2)-HA nanozyme for AKI therapy via targeting inflammatory storm and activating SIRT1/PGC-1α to restore mitochondrial homeostasis.
Su J, Wu L, Zhu H, Wang H, He X, Liang B, Cai J
Journal of advanced research 2026 Mar 17;
Journal of advanced research 2026 Mar 17;
SIRT3-mediated mitochondrial fatty acid oxidation protects against hepatic lipid deposition in fatty liver hemorrhagic syndrome.
Cao P, Chen J, Zeng C, Hu Y, Yuan J, Guo X, Cao H, Zhang C, Zhuang Y, Hu G
Poultry science 2026 Apr 7;105(7):106901
Poultry science 2026 Apr 7;105(7):106901
HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF-κB/SOD2 Signaling Pathway.
Li H, Cai S, Mu H, Chang T, Wang X, Tang T, Dong T, Zhang Y, Zhang L, Li H, Zhou L, Xiang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03828
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Sep;12(34):e03828
Electrical Vagus Nerve Stimulation Ameliorates Cardiac Ischemia and Reperfusion Injury by Improving Mitochondrial Biogenesis Through the SIRT1/PGC-1α Pathway.
Guo Y, Zhang Y, Zhang J, Bai X, Kang W, Guo Y, Zeng X
Applied biochemistry and biotechnology 2025 Nov;197(11):7314-7336
Applied biochemistry and biotechnology 2025 Nov;197(11):7314-7336
The total extract of Abelmoschus manihot (L.) medic flowers (TEA) mediated Nrf2-TFAM signalling to regulate mitochondrial antioxidant mechanism.
Song Y, Zhu X, Wang B, Li Q, Song B
Scientific reports 2025 Jan 10;15(1):1614
Scientific reports 2025 Jan 10;15(1):1614
sdRNA-D43 derived from small nucleolar RNA snoRD43 improves chondrocyte senescence and osteoarthritis progression by negatively regulating PINK1/Parkin-mediated mitophagy pathway via dual-targeting NRF1 and WIPI2.
Deng Z, Li C, Hu S, Zhong Y, Li W, Lin Z, Mo X, Li M, Xu D, Long D, Mao G, Kang Y
Cell communication and signaling : CCS 2025 Feb 11;23(1):77
Cell communication and signaling : CCS 2025 Feb 11;23(1):77
Zn(2 +) alleviates ischemia/reperfusion injury in H9c2 cells by modulating mitochondrial biogenesis and dynamics via MCU.
Wang B, Xing B, Huang L, Li X, Bian X, Xi J
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127769
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2025 Dec;92:127769
Sini-Suanzaoren decoction regulates mitochondrial biogenesis mediated by MT-SIRT1 in the treatment of insomnia rats.
Li RT, Lan BJ, Xiao ZY, Shi QH, Chen XY, Li F
World journal of psychiatry 2025 Dec 19;15(12):108867
World journal of psychiatry 2025 Dec 19;15(12):108867
NMN improves cardiac function in SIRT3 knockout mice via the SIRT1/PGC-1α pathway.
Zhao X, He M, He L, Han R, Liu Y
Scientific reports 2025 Aug 7;15(1):28975
Scientific reports 2025 Aug 7;15(1):28975
Boosting energy metabolism and biosynthesis in diverse organisms by a common bacterial salvage lipoylation protein.
Yang R, Wang Y, Kong M, Hu Z, Zhang Z, Shen K, Meng J, Zeng AP
Nature communications 2025 Aug 14;16(1):7540
Nature communications 2025 Aug 14;16(1):7540
Photobiomodulation modulates mitochondrial energy metabolism and ameliorates neurological damage in an APP/PS1 mousmodel of Alzheimer's disease.
Chen H, Li N, Liu N, Zhu H, Ma C, Ye Y, Shi X, Luo G, Dong X, Tan T, Wei X, Yin H
Alzheimer's research & therapy 2025 Apr 5;17(1):72
Alzheimer's research & therapy 2025 Apr 5;17(1):72
S100A8/A9(hi) neutrophils induce mitochondrial dysfunction and PANoptosis in endothelial cells via mitochondrial complex I deficiency during sepsis.
Wang Y, Shi Y, Shao Y, Lu X, Zhang H, Miao C
Cell death & disease 2024 Jun 28;15(6):462
Cell death & disease 2024 Jun 28;15(6):462
M6A RNA Methylation-Mediated TUG1 Stability Maintains Mitochondrial Homeostasis during Kidney Aging by Epigenetically Regulating PGC1-α Expression.
Zhu Y, Yang B, Chen S, Chen G, Zeng X, Min H, Xu L
Antioxidants & redox signaling 2024 Dec;41(16-18):993-1013
Antioxidants & redox signaling 2024 Dec;41(16-18):993-1013
NRF1-induced mmu_circ_0001388/hsa_circ_0029470 confers ferroptosis resistance in ischemic acute kidney injury via the miR-193b-3p/TCF4/GPX4 axis.
Zheng Q, Zhang D, Xing J
Life sciences 2024 Dec 1;358:123190
Life sciences 2024 Dec 1;358:123190
NRF1 Alleviated Oxidative Stress of Glioblastoma Cells by Regulating NOR1.
Wang J, Chen S, Xiang W, Zhu Q, Ren N
Folia biologica 2023;69(1):13-21
Folia biologica 2023;69(1):13-21
Hydrogen sulfide alleviates heart failure with preserved ejection fraction in mice by targeting mitochondrial abnormalities via PGC-1α.
Huang S, Chen X, Pan J, Zhang H, Ke J, Gao L, Yu Chang AC, Zhang J, Zhang H
Nitric oxide : biology and chemistry 2023 Jul 1;136-137:12-23
Nitric oxide : biology and chemistry 2023 Jul 1;136-137:12-23
Efficacy of creatine nitrate supplementation on redox status and mitochondrial function in pectoralis major muscle of preslaughter transported broilers.
Xu J, Xing T, Li J, Zhang L, Gao F
Animal biotechnology 2023 Dec;34(8):3988-3999
Animal biotechnology 2023 Dec;34(8):3988-3999
Styrax (Liquidambar orientalis Mill.) promotes mitochondrial function and reduces cardiac damage following myocardial ischemic injury: the role of the AMPK-PGC1α signaling pathway.
Mu F, Zhao J, Zhao M, Lin R, Liu K, Zhao S, Tao X, Li W, Dai Q, Xi M, Tang H, Wang J
The Journal of pharmacy and pharmacology 2023 Dec 8;75(12):1496-1508
The Journal of pharmacy and pharmacology 2023 Dec 8;75(12):1496-1508
Zerumbone attenuates the excessive proliferation of keratinocytes in psoriasis mice through regulating NLRP3/NF-κB pathway.
Lin J, Fang Y, Cao Y, Ma L, Tao M, Wang X, Li Y, Qing L
Toxicology research 2023 Aug;12(4):658-664
Toxicology research 2023 Aug;12(4):658-664
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats.
Sun J, Zhang W
PloS one 2022;17(3):e0266084
PloS one 2022;17(3):e0266084
Icaritin Attenuates Lipid Accumulation by Increasing Energy Expenditure and Autophagy Regulated by Phosphorylating AMPK.
Wu Y, Yang Y, Li F, Zou J, Wang YH, Xu MX, Wang YL, Li RX, Sun YT, Lu S, Zhang YY, Sun XD
Journal of clinical and translational hepatology 2021 Jun 28;9(3):373-383
Journal of clinical and translational hepatology 2021 Jun 28;9(3):373-383
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