Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 22803-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- IGF2BP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IGF2BP1 antibody (Cat. #22803-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references METTL3 regulates hippocampal gene transcription via N6-methyladenosine methylation in sevoflurane-induced postoperative cognitive dysfunction mouse.
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression.
Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation.
An in vitro system to silence mitochondrial gene expression.
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
EGR2-mediated regulation of m6A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization.
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs.
mTOR-autophagy promotes pulmonary senescence through IMP1 in chronic toxicity of methamphetamine.
Wilms' tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation.
A novel, liver-specific long noncoding RNA LINC01093 suppresses HCC progression by interaction with IGF2BP1 to facilitate decay of GLI1 mRNA.
PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α.
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1.
MicroRNA-873 (miRNA-873) inhibits glioblastoma tumorigenesis and metastasis by suppressing the expression of IGF2BP1.
He B, Wang J
Aging 2021 Oct 5;13(19):23108-23118
Aging 2021 Oct 5;13(19):23108-23118
Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.
Li Z, Xu Q, Huangfu N, Chen X, Zhu J
Journal of clinical laboratory analysis 2021 Nov 26;:e24019
Journal of clinical laboratory analysis 2021 Nov 26;:e24019
Stabilization of UCA1 by N6-methyladenosine RNA methylation modification promotes colorectal cancer progression.
He RZ, Jiang J, Hu X, Lei M, Li J, Luo W, Duan L, Hu Z, Mo YY, Luo DX, Peng WX
Cancer cell international 2021 Nov 22;21(1):616
Cancer cell international 2021 Nov 22;21(1):616
Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation.
Lin XT, Yu HQ, Fang L, Tan Y, Liu ZY, Wu D, Zhang J, Xiong HJ, Xie CM
eLife 2021 Nov 15;10
eLife 2021 Nov 15;10
An in vitro system to silence mitochondrial gene expression.
Cruz-Zaragoza LD, Dennerlein S, Linden A, Yousefi R, Lavdovskaia E, Aich A, Falk RR, Gomkale R, Schöndorf T, Bohnsack MT, Richter-Dennerlein R, Urlaub H, Rehling P
Cell 2021 Nov 11;184(23):5824-5837.e15
Cell 2021 Nov 11;184(23):5824-5837.e15
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q
Cell research 2021 Mar;31(3):345-361
Cell research 2021 Mar;31(3):345-361
EGR2-mediated regulation of m6A reader IGF2BP proteins drive RCC tumorigenesis and metastasis via enhancing S1PR3 mRNA stabilization.
Ying Y, Ma X, Fang J, Chen S, Wang W, Li J, Xie H, Wu J, Xie B, Liu B, Wang X, Zheng X, Xie L
Cell death & disease 2021 Jul 29;12(8):750
Cell death & disease 2021 Jul 29;12(8):750
In vivo structural characterization of the SARS-CoV-2 RNA genome identifies host proteins vulnerable to repurposed drugs.
Sun L, Li P, Ju X, Rao J, Huang W, Ren L, Zhang S, Xiong T, Xu K, Zhou X, Gong M, Miska E, Ding Q, Wang J, Zhang QC
Cell 2021 Apr 1;184(7):1865-1883.e20
Cell 2021 Apr 1;184(7):1865-1883.e20
mTOR-autophagy promotes pulmonary senescence through IMP1 in chronic toxicity of methamphetamine.
Zhu MJ, Liu BY, Shi L, Wang X, Wang Y
Journal of cellular and molecular medicine 2020 Oct;24(20):12082-12093
Journal of cellular and molecular medicine 2020 Oct;24(20):12082-12093
Wilms' tumour 1-associating protein inhibits endothelial cell angiogenesis by m6A-dependent epigenetic silencing of desmoplakin in brain arteriovenous malformation.
Wang LJ, Xue Y, Li H, Huo R, Yan Z, Wang J, Xu H, Wang J, Cao Y, Zhao JZ
Journal of cellular and molecular medicine 2020 May;24(9):4981-4991
Journal of cellular and molecular medicine 2020 May;24(9):4981-4991
A novel, liver-specific long noncoding RNA LINC01093 suppresses HCC progression by interaction with IGF2BP1 to facilitate decay of GLI1 mRNA.
He J, Zuo Q, Hu B, Jin H, Wang C, Cheng Z, Deng X, Yang C, Ruan H, Yu C, Zhao F, Yao M, Fang J, Gu J, Zhou J, Fan J, Qin W, Yang XR, Wang H
Cancer letters 2019 May 28;450:98-109
Cancer letters 2019 May 28;450:98-109
PTBP3 contributes to colorectal cancer growth and metastasis via translational activation of HIF-1α.
Hou P, Chen F, Yong H, Lin T, Li J, Pan Y, Jiang T, Li M, Chen Y, Song J, Zheng J, Bai J
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):301
Journal of experimental & clinical cancer research : CR 2019 Jul 10;38(1):301
The LINC01138 drives malignancies via activating arginine methyltransferase 5 in hepatocellular carcinoma.
Li Z, Zhang J, Liu X, Li S, Wang Q, Di Chen, Hu Z, Yu T, Ding J, Li J, Yao M, Fan J, Huang S, Gao Q, Zhao Y, He X
Nature communications 2018 Apr 20;9(1):1572
Nature communications 2018 Apr 20;9(1):1572
Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1.
Panda AC, Grammatikakis I, Kim KM, De S, Martindale JL, Munk R, Yang X, Abdelmohsen K, Gorospe M
Nucleic acids research 2017 Apr 20;45(7):4021-4035
Nucleic acids research 2017 Apr 20;45(7):4021-4035
MicroRNA-873 (miRNA-873) inhibits glioblastoma tumorigenesis and metastasis by suppressing the expression of IGF2BP1.
Wang RJ, Li JW, Bao BH, Wu HC, Du ZH, Su JL, Zhang MH, Liang HQ
The Journal of biological chemistry 2015 Apr 3;290(14):8938-48
The Journal of biological chemistry 2015 Apr 3;290(14):8938-48
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IGF2BP1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IGF2BP1. This antibody recognizes human, mouse, rat antigen. The IGF2BP1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
