orb1826206

antibody from Biorbyt
Targeting: KCNIP2 KCHIP2
Provider product page for orb1826206
Immunohistochemistry

Antibody data

Product number
orb1826206 - Provider product page
Provider
Biorbyt
Product name
KChIP2 Antibody / KCNIP2
Antibody type
Monoclonal
Description
In the brain and heart, rapidly inactivating (A-type) voltage-gated potassium (Kv) currents control the excitability of neurons and cardiac myocytes. KChIPs are Kv channel-interacting proteins that bind to the cytoplasmic amino termini of Kv4Alpha-subunits and are integral components of native Kv4 channel complexes. KChIP family members include KChIP1 expressed in brain, KChIP2 expressed in heart, brain, and lung, and KChIP3 (previously identified as calsenilin) expressed in brain and testis. In rat brain, KChIP1 colocalizes with Kv4.3 in granule cells and KChIP2 colocalizes with Kv4.2 in both neocoritcal and subcortical structures. The KChIPs are members of the recoverin/neuronal calcium sensor-1 subfamily of calcium-binding proteins and show 99% nucleotide homology to DREAM, suggesting that KChIPs may have activity beyond modulation of Kv4 channels.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
KCNIP2/7589
Vial size
100 ug
Storage
Aliquot the KChIP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
KCNIP2 protein structure - orb1826206 shown in red.