orb2634911

antibody from Biorbyt
Targeting: MYCL bHLHe38, LMYC, MYCL1
Provider product page for orb2634911
Western blot
ELISA
Immunocytochemistry
Flow cytometry

Antibody data

Product number
orb2634911 - Provider product page
Provider
Biorbyt
Product name
L-Myc Antibody / MYCL1
Antibody type
Monoclonal
Description
Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas, and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PCRP-MYCL-2D5
Vial size
20 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
MYCL protein structure - orb2634911 shown in red.