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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Product number
- MA1-35782 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- RBP1 Monoclonal Antibody (G4E4)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- G4E4 recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver.
- Reactivity
- Human, Mouse, Rat, Goat, Rabbit
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- G4E4
- Vial size
- 100 µg
- Concentration
- 0.1 mg/mL
- Storage
- 4° C
Submitted references Transforming growth factor-beta and substrate stiffness regulate portal fibroblast activation in culture.
cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.
cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.
Li Z, Dranoff JA, Chan EP, Uemura M, Sévigny J, Wells RG
Hepatology (Baltimore, Md.) 2007 Oct;46(4):1246-56
Hepatology (Baltimore, Md.) 2007 Oct;46(4):1246-56
cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.
Shan L, He M, Yu M, Qiu C, Lee NH, Liu ET, Snyderwine EG
Carcinogenesis 2002 Oct;23(10):1561-8
Carcinogenesis 2002 Oct;23(10):1561-8
cDNA microarray profiling of rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 7,12-dimethylbenz[a]anthracene.
Shan L, He M, Yu M, Qiu C, Lee NH, Liu ET, Snyderwine EG
Carcinogenesis 2002 Oct;23(10):1561-8
Carcinogenesis 2002 Oct;23(10):1561-8
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