Antibody data
- Antibody Data
- Antigen structure
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- Product number
- PABL-103 - Provider product page
- Provider
- Creative Biolabs
- Product name
- Human Anti-GIPR Recombinant Antibody (clone Gipg013)
- Antibody type
- Monoclonal
- Description
- Recombinant Human Antibody (Gipg013) is capable of binding to GIPR, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-GIPR mAb and CH1-3 region of human IgG1 and a light chain (LC) encoding VL from anti-GIPR mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. This antibody is a specific competitive antagonist with equally high potencies to mouse, rat, dog, and human GIP receptors with a Ki of 7 nm for the human GIPr. Gipg013 antagonizes the GIP receptor and inhibits GIP-induced insulin secretion in vitro and in vivo.
- Reactivity
- Human
- Host
- Human
- Antibody clone number
- Gipg013
- Storage
- Centrifuge briefly prior to opening vial. Store at +4¡ãC short term (1-2 weeks). Aliquot and store at -20¡ãC long term. Avoid repeated freeze/thaw cycles.
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