Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [2]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- NB100-481 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-481, RRID:AB_10000573
- Product name
- Rabbit Polyclonal BP1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. This is specific for human BP1 (DLX4 variant 1). Berg PE, Kirolikar S. DLX4 (distal-less homeobox 4). Atlas Genet Cytogenet Oncol Haematol. January 2011. URL : http://AtlasGeneticsOncology.org/Genes/DLX4ID49827ch17q21.html
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 1 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references Homeoprotein DLX4 expression is increased in inflammatory breast cancer cases from an urban African-American population.
Identification and molecular characterization of a new member of the peritrophic membrane proteins from the meadow moth, loxostege sticticalis.
Identification and molecular characterization of a new member of the peritrophic membrane proteins from the meadow moth, loxostege sticticalis.
BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer.
BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer.
BP1 Homeoprotein Enhances Metastatic Potential in ER-negative Breast Cancer.
BP1 Homeoprotein Enhances Metastatic Potential in ER-negative Breast Cancer.
Genome-wide analysis of BP1 transcriptional targets in breast cancer cell line Hs578T.
Genome-wide analysis of BP1 transcriptional targets in breast cancer cell line Hs578T.
BP1 transcriptionally activates bcl-2 and inhibits TNFalpha-induced cell death in MCF7 breast cancer cells.
Jeong J, Naab TJ, Fernandez AI, Ongkeko MS, Makambi KH, Blancato JK
Oncotarget 2018 Jul 27;9(58):31253-31263
Oncotarget 2018 Jul 27;9(58):31253-31263
Identification and molecular characterization of a new member of the peritrophic membrane proteins from the meadow moth, loxostege sticticalis.
Yin J, Wei ZJ, Li KB, Cao YZ, Guo W
International journal of biological sciences 2010 Sep 6;6(5):491-8
International journal of biological sciences 2010 Sep 6;6(5):491-8
Identification and molecular characterization of a new member of the peritrophic membrane proteins from the meadow moth, loxostege sticticalis.
Yin J, Wei ZJ, Li KB, Cao YZ, Guo W
International journal of biological sciences 2010 Sep 6;6(5):491-8
International journal of biological sciences 2010 Sep 6;6(5):491-8
BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer.
Kluk BJ, Fu Y, Formolo TA, Zhang L, Hindle AK, Man YG, Siegel RS, Berg PE, Deng C, McCaffrey TA, Fu SW
International journal of biological sciences 2010 Sep 10;6(5):513-24
International journal of biological sciences 2010 Sep 10;6(5):513-24
BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer.
Kluk BJ, Fu Y, Formolo TA, Zhang L, Hindle AK, Man YG, Siegel RS, Berg PE, Deng C, McCaffrey TA, Fu SW
International journal of biological sciences 2010 Sep 10;6(5):513-24
International journal of biological sciences 2010 Sep 10;6(5):513-24
BP1 Homeoprotein Enhances Metastatic Potential in ER-negative Breast Cancer.
Fu Y, Lian Y, Kim KS, Zhang L, Hindle AK, Brody F, Siegel RS, McCaffrey TA, Fu SW
Journal of Cancer 2010 Jun 24;1:54-62
Journal of Cancer 2010 Jun 24;1:54-62
BP1 Homeoprotein Enhances Metastatic Potential in ER-negative Breast Cancer.
Fu Y, Lian Y, Kim KS, Zhang L, Hindle AK, Brody F, Siegel RS, McCaffrey TA, Fu SW
Journal of Cancer 2010 Jun 24;1:54-62
Journal of Cancer 2010 Jun 24;1:54-62
Genome-wide analysis of BP1 transcriptional targets in breast cancer cell line Hs578T.
Song Y, Dang C, Fu Y, Lian Y, Hottel J, Li X, McCaffrey T, Fu SW
International journal of biological sciences 2009;5(1):1-12
International journal of biological sciences 2009;5(1):1-12
Genome-wide analysis of BP1 transcriptional targets in breast cancer cell line Hs578T.
Song Y, Dang C, Fu Y, Lian Y, Hottel J, Li X, McCaffrey T, Fu SW
International journal of biological sciences 2009;5(1):1-12
International journal of biological sciences 2009;5(1):1-12
BP1 transcriptionally activates bcl-2 and inhibits TNFalpha-induced cell death in MCF7 breast cancer cells.
Stevenson HS, Fu SW, Pinzone JJ, Rheey J, Simmens SJ, Berg PE
Breast cancer research : BCR 2007;9(5):R60
Breast cancer research : BCR 2007;9(5):R60
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: BP1 Antibody [NB100-481] - Effect of BP1 on TNFalpha-induced cell death. Western blot analysis of Beta Protein 1 (BP1) protein expression in MCF7/EV cell lines and MCF7/BP1 cell lines. Image collected and cropped by CiteAb from the following publication (http://breast-cancer-research.biomedcentral.com/articles/10.1186/bcr1766), licensed under a CC-BY licence.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: BP1 Antibody [NB100-481] - Detection of MDA-MB-231 cell lysates.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunoprecipitation: BP1 Antibody [NB100-481] - Antibody diluted 1:5,000 2. BP1-specific band after immunoprecipitation of 850 ug of cell extract using anti-BP1 (NB100-481) antibody diluted 1:1,000 3. Negative control for IP in lane 2: cell extract incubated with 50ul of Protein A/G beads.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: BP1 Antibody [NB100-481] - Top Panel: BP1 antibody detected in breast cancer cells. Bottom Panel: Staining of normal breast tissue.