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- Antigen structure
- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 66099-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- EXOSC2 antibody
- Antibody type
- Monoclonal
- Description
- EXOSC2 antibody (Cat. #66099-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1G8B1
- Vial size
- 20ul, 150ul
Submitted references Elucidating AML ribosome biogenesis reshaping prognostic assessment and immune microenvironment integrated single-cell and bulk RNA analysis.
Apigenin inhibits endothelial-to-mesenchymal transition of coronary artery endothelial cells and myocardial fibrosis by regulating ribosome biogenesis through GTPBP4 modulation.
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.
The melatonin-FTO-ATF4 signaling pathway protects granulosa cells from cisplatin-induced chemotherapeutic toxicity by suppressing ferroptosis.
PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer.
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Metformin Exhibits an Attractive Antineoplastic Effect on Human Endometrial Cancer by Regulating the Hippo Signaling Pathway.
FGF2 Is Protective Towards Cisplatin-Induced KGN Cell Toxicity by Promoting FTO Expression and Autophagy.
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
FTO protects human granulosa cells from chemotherapy-induced cytotoxicity.
The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest.
Chen X, Feng A, Chen F, Zeng J, Chen M
Frontiers in immunology 2025;16:1644671
Frontiers in immunology 2025;16:1644671
Apigenin inhibits endothelial-to-mesenchymal transition of coronary artery endothelial cells and myocardial fibrosis by regulating ribosome biogenesis through GTPBP4 modulation.
Hu X, Yang Z, Tang R, Lv Z, Zou T, Dou Y, Li H
Human cell 2025 Sep 12;38(6):157
Human cell 2025 Sep 12;38(6):157
FTO attenuates the cytotoxicity of cisplatin in KGN granulosa cell-like tumour cells by regulating the Hippo/YAP1 signalling pathway.
Wang R, Cheng F, Yang X
Journal of ovarian research 2024 Mar 15;17(1):62
Journal of ovarian research 2024 Mar 15;17(1):62
The melatonin-FTO-ATF4 signaling pathway protects granulosa cells from cisplatin-induced chemotherapeutic toxicity by suppressing ferroptosis.
Wang R, Geng J
Journal of assisted reproduction and genetics 2024 Dec;41(12):3503-3516
Journal of assisted reproduction and genetics 2024 Dec;41(12):3503-3516
PIWI-interacting RNA-17458 is oncogenic and a potential therapeutic target in cervical cancer.
Liu L, Li L, Zu W, Jing J, Liu G, Sun T, Xie Q
Journal of Cancer 2023;14(9):1648-1659
Journal of Cancer 2023;14(9):1648-1659
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JN, Dos Santos Souza C, Zhang S, Castelli L, Hautbergue G, Azzouz M, Gordon D, Krogan N, Ferraiuolo L, Snyder MP, Shaw PJ, Rehwinkel J, Cooper-Knock J
Life science alliance 2023 Jan;6(1)
Life science alliance 2023 Jan;6(1)
Metformin Exhibits an Attractive Antineoplastic Effect on Human Endometrial Cancer by Regulating the Hippo Signaling Pathway.
Wang M, Zhang Q, Li Y, Jin L, Fang Z
Journal of oncology 2022;2022:5824617
Journal of oncology 2022;2022:5824617
FGF2 Is Protective Towards Cisplatin-Induced KGN Cell Toxicity by Promoting FTO Expression and Autophagy.
Wang R, Wang L, Wang L, Cui Z, Cheng F, Wang W, Yang X
Frontiers in endocrinology 2022;13:890623
Frontiers in endocrinology 2022;13:890623
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication.
Moll T, Odon V, Harvey C, Collins MO, Peden A, Franklin J, Graves E, Marshall JNG, Souza CDS, Zhang S, Azzouz M, Gordon D, Krogan N, Ferraiuolo L, Snyder MP, Shaw PJ, Rehwinkel J, Cooper-Knock J
bioRxiv : the preprint server for biology 2022 Mar 7;
bioRxiv : the preprint server for biology 2022 Mar 7;
FTO protects human granulosa cells from chemotherapy-induced cytotoxicity.
Wang R, Wang W, Wang L, Yuan L, Cheng F, Guan X, Zheng N, Yang X
Reproductive biology and endocrinology : RB&E 2022 Feb 26;20(1):39
Reproductive biology and endocrinology : RB&E 2022 Feb 26;20(1):39
The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest.
Trendel J, Schwarzl T, Horos R, Prakash A, Bateman A, Hentze MW, Krijgsveld J
Cell 2019 Jan 10;176(1-2):391-403.e19
Cell 2019 Jan 10;176(1-2):391-403.e19
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 66099-1-Ig(EXOSC2 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using EXOSC2 antibody 66099-1-lg at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red).
- Sample type
- cell line
