17-0494-41

antibody from Invitrogen Antibodies
Targeting: ITGA3 CD49c, GAP-B3, MSK18, VCA-2, VLA3a
Provider product page for 17-0494-41

Antibody data

Product number
17-0494-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD49c (Integrin alpha 3) Monoclonal Antibody (P1B5), APC, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: This P1B5 monoclonal antibody reacts with human CD49c (also known as Integrin alpha 3). Integrins constitute a family of cell surface receptors that mediate adhesion between cells or between a cell and the extracellular matrix. These proteins are heterodimers consisting of two distinct subunits, alpha and beta. Integrins are expressed on hematopoietic, non-hematopoietic, and cancer cells. Integrin-mediated adhesion is regulated by changes in ligand affinity (or activation), cell shape, and integrin clustering and diffusion. Integrin alpha 3 forms a complex with the common beta 1 subunit to form the alpha3beta1 integrin. Studies have demonstrated the involvement of this integrin in wound healing and epithelial migration. The P1B5 monoclonal antibody has been reported to affect adhesion to type I and VI collagens, as well as fibronectin and laminin. Applications Reported: This P1B5 antibody has been reported for use in flow cytometric analysis. Applications Tested: This P1B5 antibody has been pre-titrated and tested by flow cytometric analysis of HeLa cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 µm post-manufacturing filtered.
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
P1B5
Vial size
25 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
ITGA3 protein structure - 17-0494-41 shown in red.