APR02078G

antibody from Leading Biology

Targeting: ITGA3 CD49c, GAP-B3, MSK18, VCA-2, VLA3a

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

APR02078G

Provider

Leading Biology

Product name

ITGA3 / CD49c Antibody (Internal)

Antibody type

Polyclonal

Description

Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha- 3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Reactivity

Human, Simian

Host

Rabbit

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.