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- Antigen structure
- References [16]
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- Product number
- 21992-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21992-1-AP, RRID:AB_10953527
- Product name
- Integrin Alpha 3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Integrin Alpha 3 antibody (Cat. #21992-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references OTUD1 delays wound healing by regulating endothelial function and angiogenesis in diabetic mice.
CD151 Promotes Cancer Progression in Triple-Negative Breast Cancer by Inducing EMT through the MAPK Signaling Pathway.
High molecular weight laminarin/AgNPs-impregnated PVA based in situ hydrogels accelerated diabetic wound healing.
Exosomal integrin alpha 3 promotes epithelial ovarian cancer cell migration via the S100A7/p-ERK signaling pathway.
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII.
KBU2046 exerts inhibition on chemokine gradient-mediated motility of esophageal squamous cell carcinoma through reducing integrin expression.
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner.
Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis.
Unveiling the therapeutic potential: KBU2046 halts triple-negative breast cancer cell migration by constricting TGF-β1 activation in vitro.
Engagement of α(3)β(1) and α(2)β(1) integrins by hypervirulent Streptococcus agalactiae in invasion of polarized enterocytes.
Elevated ITGA3 expression serves as a novel prognostic biomarker and regulates tumor progression in cervical cancer.
Mimicking Tumor Metastasis Using a Transwell-Integrated Organoids-On-a-Chip Platform.
Simultaneous targeting and suppression of heat shock protein 60 to overcome heat resistance and induce mitochondrial death of tumor cells in photothermal immunotherapy.
Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis.
High Expression of Integrin α3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer.
miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2.
Zhang J, Li W, Liu Y, Zheng J, Liu G, He M, Zheng Z, Zhu M, Cho N, Liang G, Han X, Ying H, Shi Q
Journal of advanced research 2026 Feb;80:1063-1081
Journal of advanced research 2026 Feb;80:1063-1081
CD151 Promotes Cancer Progression in Triple-Negative Breast Cancer by Inducing EMT through the MAPK Signaling Pathway.
Lv H, Zhang B, Weng X, Li Y, Deng C, Wang R, Shi L, Yin Y
Breast cancer (Dove Medical Press) 2025;17:455-470
Breast cancer (Dove Medical Press) 2025;17:455-470
High molecular weight laminarin/AgNPs-impregnated PVA based in situ hydrogels accelerated diabetic wound healing.
Abbasi YF, Guo X, Chen Y, Li J, Xu X, Li Y, Cun D, Bera H, Yang M
Carbohydrate polymers 2025 Nov 1;367:123991
Carbohydrate polymers 2025 Nov 1;367:123991
Exosomal integrin alpha 3 promotes epithelial ovarian cancer cell migration via the S100A7/p-ERK signaling pathway.
Yin Z, Ma J, Adu-Amankwaah J, Xie G, Wang Y, Tai W, Sun Z, Huang C, Chen G, Fu T, Zhang B, Zhou X
Acta biochimica et biophysica Sinica 2025 Mar 7;57(6):1006-1019
Acta biochimica et biophysica Sinica 2025 Mar 7;57(6):1006-1019
Discovery and Functional Characterization of a Recombinant Fragment of Human Collagen Type XVII.
Piao L, Li J, Li X, Su Y, Yuan X, Chang S, Cheng X, Fu S, Kong R
Journal of agricultural and food chemistry 2025 Mar 19;73(11):6724-6735
Journal of agricultural and food chemistry 2025 Mar 19;73(11):6724-6735
KBU2046 exerts inhibition on chemokine gradient-mediated motility of esophageal squamous cell carcinoma through reducing integrin expression.
Li K, Chen J, Li W, Zhang Z, Xue Y, Zheng Y, Zhang Y, Zhang C, Bergan R, Zhao L
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167800
Biochimica et biophysica acta. Molecular basis of disease 2025 Jun;1871(5):167800
ITGA3 promotes pancreatic cancer progression through HIF1α- and c-Myc-driven glycolysis in a collagen I-dependent autocrine manner.
Li R, Ji Q, Fu S, Gu J, Liu D, Wang L, Yuan X, Wen Y, Dai C, Li H
Cancer gene therapy 2025 Feb;32(2):240-253
Cancer gene therapy 2025 Feb;32(2):240-253
Nephronectin (NPNT) is a Crucial Determinant of Idiopathic Pulmonary Fibrosis: Modulating Cellular Senescence via the ITGA3/YAP1 Signaling Axis.
Guo J, Wang Y, Liu Q, Luo Z, Tian X, Wang Y, Liu Y, Ning Z, Guo Y, Gao H, Wang X, Feng J, Liu M, Saifullina D, Zhang Y, Pan T, Bian Y, Ban T, Li T, Gu Y, Liang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e01956
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Aug;12(32):e01956
Unveiling the therapeutic potential: KBU2046 halts triple-negative breast cancer cell migration by constricting TGF-β1 activation in vitro.
Chen J, Dai S, Zhang G, Wei S, Zhao X, Zheng Y, Wang Y, Wang X, Liu Y, Zhao L
Oncology research 2024;32(11):1791-1802
Oncology research 2024;32(11):1791-1802
Engagement of α(3)β(1) and α(2)β(1) integrins by hypervirulent Streptococcus agalactiae in invasion of polarized enterocytes.
De Gaetano GV, Lentini G, Coppolino F, Famà A, Pietrocola G, Beninati C
Frontiers in microbiology 2024;15:1367898
Frontiers in microbiology 2024;15:1367898
Elevated ITGA3 expression serves as a novel prognostic biomarker and regulates tumor progression in cervical cancer.
Tan W, Chen G, Ci Q, Deng Z, Gu R, Yang D, Dai F, Liu H, Cheng Y
Scientific reports 2024 Nov 7;14(1):27063
Scientific reports 2024 Nov 7;14(1):27063
Mimicking Tumor Metastasis Using a Transwell-Integrated Organoids-On-a-Chip Platform.
Chen M, Shan H, Tao Q, Hu R, Sun Q, Zheng M, Chen Z, Lin Q, Yin M, Zhao S, Chen X, Chen Z
Small (Weinheim an der Bergstrasse, Germany) 2024 Jul;20(27):e2308525
Small (Weinheim an der Bergstrasse, Germany) 2024 Jul;20(27):e2308525
Simultaneous targeting and suppression of heat shock protein 60 to overcome heat resistance and induce mitochondrial death of tumor cells in photothermal immunotherapy.
Meng Y, Wen T, Liu X, Yang A, Meng J, Liu J, Wang J, Xu H
Materials today. Bio 2024 Dec;29:101282
Materials today. Bio 2024 Dec;29:101282
Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis.
Bae E, Huang P, Müller-Greven G, Hambardzumyan D, Sloan AE, Nowacki AS, Marko N, Carlin CR, Gladson CL
Nature communications 2022 Jul 25;13(1):4268
Nature communications 2022 Jul 25;13(1):4268
High Expression of Integrin α3 Predicts Poor Prognosis and Promotes Tumor Metastasis and Angiogenesis by Activating the c-Src/Extracellular Signal-Regulated Protein Kinase/Focal Adhesion Kinase Signaling Pathway in Cervical Cancer.
Du Q, Wang W, Liu T, Shang C, Huang J, Liao Y, Qin S, Chen Y, Liu P, Liu J, Yao S
Frontiers in oncology 2020;10:36
Frontiers in oncology 2020;10:36
miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2.
Yang Z, Li R, Ao J, Wa QD, Zhang Y, Chen L, Wen J, Chen B, Pan W, Li B, Tian XB
International journal of molecular medicine 2018 Dec;42(6):3115-3124
International journal of molecular medicine 2018 Dec;42(6):3115-3124
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Integrin alpha-3 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human Integrin alpha-3. This antibody recognizes human antigen. The Integrin alpha-3 antibody has been validated for the following applications: ELISA, WB analysis.
